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Browsing Research Articles (Immunology) by Issue Date
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Cassol, Sharon; Gordon, Michelle; De Oliveira, Tulio; Bishop, Karen; Coovadia, H.M.; Madurai, L.; Engelbrecht, Susan; Janse van Rensburg, Estrelita; Mosam, A.; Smith, A.
(American Society for Microbiology, 2003-02)
The KwaZulu-Natal region of South Africa is experiencing an explosive outbreak of Human Immunodeficiency Virus Type 1 (HIV-1) Subtype C infections. Understanding the genetic diversity of C viruses and the biological ...
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Cassol, Sharon; De Oliveira, Tulio; Engelbrecht, Susan; Janse van Rensburg, Estrelita; Gordon, Michelle; Bishop, Karen; Zur Megede, Jan; Barnett, Susan W.
(American Society for Microbiology, 2003-09)
Naturally occurring polymorphisms in the protease of human immunodeficiency virus type 1 (HIV-1)subtype C would be expected to lead to adaptive (compensatory) changes in protease cleavage sites. To test this hypothesis, ...
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De Oliveira, Tulio; Deforche, Koen; Cassol, Sharon; Salminen, M.; Paraskevis, D.; Seebreghts, C.; Snoeck, J.; Janse van Rensburg, Estrelita; Wensing, A.M.J.; Van der Vijver, D.A.; Boucher, C.A.; Camacho, R.; Vandamme, Anne-Mieke
(Oxford University Press, 2005-10-01)
Motivation: Genetic analysis of HIV-1 is important not only for vaccine development, but also to guide treatment strategies, track the emergence of new viral variants and ensure that diagnostic assays are contemporary and ...
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Anderson, Ronald; Steel, Helen C.; Cockeran, Riana; Smith, Anthony Marius; Von Gottberg, Anne; De Gouveia, L.; Brink, Andries J.; Klugman, Keith P.; Mitchell, Timothy J.; Feldman, Charles
(Oxford University Press, 2007-02)
Please refer to abstract in article
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Delport, Wayne; Van der Merwe, Schalk Willem
(Elsevier, 2007-04)
Although much is known about the virulence of Helicobacter pylori, the transmission pathways for this bacterium are still unresolved. Transmission has been addressed through: (1) prevalence within families; (2) detection ...
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Tintinger, Gregory Ronald; Theron, Annette J.; Anderson, Ronald; Potjo, Moliehi
(Elsevier, 2007-06-15)
Please refer to abstract in article
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Danaviah, S.; Govender, S.; Cassol, Sharon
(Lippincott Williams and Wilkins, 2007-07)
Approximately 2 million South Africans are HIV/TB coinfected, and many develop skeletal disease. The resurgence of spinal tuberculosis, including atypical forms, is due largely to HIV-associated immune suppression. We ...
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Steel, Helen C.; Tintinger, Gregory Ronald; Theron, Annette J.; Anderson, Ronald
(Blackwell, 2007-10)
Please refer to abstract in article
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Anderson, Ronald; Steel, Helen C.; Cockeran, Riana; Von Gottberg, Anne; De Gouveia, L.; Klugman, Keith P.; Mitchell, Timothy J.; Feldman, Charles
(Oxford University Press, 2007-11)
OBJECTIVES: To compare the effects of subinhibitory concentrations of amoxicillin, ceftriaxone, azithromycin, clarithromycin, erythromycin, telithromycin, clindamycin, ciprofloxacin, moxifloxacin, tobramycin and doxycycline ...
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Feldman, Charles; Anderson, Ronald
(Health & Medical Publishing Group, 2007-11)
The pneumococcus remains an extremely important cause of morbidity and mortality worldwide. While the micro-organism has a number of significant virulence mechanisms, many recent studies have focused on pneumolysin, which ...
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Tintinger, Gregory Ronald; Steel, Helen C.; Theron, Annette J.; Anderson, Ronald
(Dove Medical Press, 2008)
Unlike most other effector cells of the innate, as well as the adaptive immune systems,
the neutrophil is a relatively undiscerning aggressor with scant regard for damage limitation.
Although this highly combative, ...
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Pathak, Arvind P.; Hochfeld, Warren Ernst; Goodman, Simon L.; Pepper, Michael Sean
(Springer, 2008)
Abundant preclinical and indirect clinical data have for several decades convincingly supported the notion that anti-angiogenesis is an effective strategy for the inhibition of tumor growth. The recent success achieved in ...
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Green, Robin J.; Feldman, Charles; Schoub, Barry D.; Richards, Guy A.; Madhi, Shabir A.; Zar, Heather J.; Lalloo, Umesh G.
(Health and Medical Publishing Group, 2008-03)
OBJECTIVE: The South African Thoracic Society, in conjunction
with interested stakeholders, published a Guideline for
Influenza Management in Adults in 1999. This year the South
African Thoracic Society (SATS) identified ...
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Schlaudraff, Kai-Uwe; Bezzola, Thierry; Montandon, Denys; Pepper, Michael Sean; Pittet, Brigitte
(Elsevier, 2008-11)
BACKGROUND: Leeches are commonly used in reconstructive surgery for the treatment of venous congestion in flaps. Documented mechanisms of action are: 1) injection of the anticoagulant hirudin; 2) active suction of blood; ...
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Jordaan, Donrich Willem; Woodrow, Christopher; Pepper, Michael Sean
(Juta Law, 2009)
Stem cell banking is a complex and controversial subject. There are currently three private stem cell banks in South Africa. At present, South Africa does not have a public stem cell bank. The de facto legal vacuum in which ...
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Feldman, Charles; Anderson, Ronald
(Federation of Infectious Diseases Societies of South Africa, 2009)
In addition to their conventional antimicrobial activity, the macrolide group of antibiotics are known to have a number of anti-inflammatory/
immunomodulatory activities, which may be of benefit to patients with chronic ...
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Fritz, Elongo Lekunze; Van der Merwe, Schalk Willem
(Health and Medical Publishing Group, 2009-05)
Gastric cancer is one of the most common forms of cancer worldwide, with an estimated 930 000 new cases diagnosed each year. It is thought to be more prevalent in men than in women. In South Africa the latest cancer ...
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Alcantara, Luiz Carlos Junior; Cassol, Sharon; Libin, Pieter; Deforche, Koen; Pybus, Oliver G.; Van Ranst, Marc; Galvao-Castro, Bernardo; Vandamme, Anne-Mieke; De Oliveira, Tulio
(Oxford University Press, 2009-07)
Human immunodeficiency virus type-1 (HIV-1), hepatitis B and C and other rapidly evolving viruses are characterized by extremely high levels of genetic diversity. To facilitate diagnosis and the development of prevention ...
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Pepper, Michael Sean
(Health and Medical Publishing Group, 2009-07)
Every innovation in medicine is met with a mixture of excitement, expectation and a certain degree of apprehension. Nowhere is this more apparent than in the field of cellbased therapy, i.e. the application of cells to ...
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Potjo, Moliehi; Cockeran, Riana; Theron, Annette J.; Feldman, Charles; Anderson, Ronald
(Molecular Diversity Preservation International, 2010)
Moxifloxacin is useful in the treatment of respiratory infections, including
community-acquired pneumonia, and also shows promise in the treatment of tuberculosis, a clinical setting which necessitates extended administration ...