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Browsing Haematology by Type "Article"
Now showing items 1-20 of 26
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(MDPI Publishing, 2020-12)This study probed the di erential utilization of P2Y1 and P2Y12 receptors in mobilizing CD62P (P-selectin) from intracellular granules following activation of human platelets with adenosine 50-diphosphate (ADP, 100 mol L1) ...
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(Hindawi Publishing Corporation, 2017-11-07)Acute myeloid leukemia (AML) is characterized by proliferation of the myeloid lineage and accumulation of immature hematopoietic cells in the bone marrow and is typified by marked heterogeneity both in response to treatment ...
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(Society of Medical Laboratory Technologists of South Africa, 2017-06)This study aimed to examine the number and type of cancer diagnoses made based on bone marrow aspirates (BMA) using morphology and/or histology, over a three year period. All the data collected (2012-2015) was obtained ...
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(Frontiers Media, 2018-11-20)Although the inclusion of the cationic amphiphilic, anti-mycobacterial agent, clofazimine, in the chemotherapeutic regimens of patients with multidrug-resistant tuberculosis (TB) has contributed to improved outcomes, ...
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(AOSIS Open Journals, 2018-01-31)The purpose of this study was to develop a real time polymerase chain reaction (PCR) assay for the detection of the JAK2 V617F mutation that could be used in diagnostic laboratories. Sanger sequencing and a newly developed ...
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(Taylor and Francis, 2022)Please read abstract in the article.
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(Wiley Open Access, 2020-08)BACKGROUND : Fanconi anemia (FA) is phenotypically diverse, hereditary condition associated with bone marrow failure, multiple physical abnormalities, and an increased susceptibility to the development of malignancies. ...
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(Health and Medical Publishing Group, 2017-09)BACKGROUND. The number of peripheral blood and endometrial natural killer cells varies greatly during implantation and the first trimester of pregnancy and is thought to play a role in the maintenance of a healthy pregnancy. ...
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(AOSIS, 2022-08-12)BACKGROUND : Haemoglobinopathies are one of the most common inherited diseases worldwide. Quantification of haemoglobin A2 is necessary for the diagnosis of the beta thalassaemia trait. In this context, it is important ...
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(Public Library of Science, 2013-12-20)BACKGROUND: Point of Care testing (POCT) provides on-site, rapid, accessible results. With current South African anti-retroviral treatment guidelines, up to 4 fingersticks /patient/clinic visit could be required if utilizing ...
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(In House Publications, 2016)Haematological abnormalities are frequently encountered in the obstetric patient. Cytopenias are common, with anaemia and thrombocytopenia predominating. Many other haematological conditions are seen during pregnancy, ...
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(Health and Medical Publishing Group, 2019-09)Human immunodeficiency virus (HIV) infection not only leads to a compromised immune system, but also disrupts normal haematopoiesis, resulting in the frequent manifestation of cytopenias (anaemia, thrombocytopenia and ...
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(Health and Medical Publishing Group, 2019-09)BACKGROUND: Optimal care of patients with inherited bleeding disorders requires that bleeding episodes are treated early, or still better prevented, through extension of patient care beyond hospital-based treatment to ...
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(Public Library of Science, 2016-08-24)INTRODUCTION HIV-infected patients require antiretroviral treatment for life. To improve access to care, CD4 enumeration and viral load tests have been redesigned to be used as point-of-care techniques using finger-stick ...
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(South African Heart Association, 2020-11)COVID-19 is associated with a hypercoagulable state that may present as pulmonary thrombosis, pulmonary embolism, and venous and arterial thrombosis. Suggested pathogenesis include direct infection of the endothelial cell ...
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(MDPI, 2023-02)With the global rollout of mother-to-child prevention programs for women living with HIV, vertical transmission has been all but eliminated in many countries. However, the number of children who are exposed in utero to HIV ...
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(Society of Medical Laboratory Technologists of South Africa, 2010-06)INTRODUCTION: Pre-analytical variability currently represents the most important source of errors that can lead to inaccurate patient results in monitoring of patients being treated with oral anticoagulant therapy. The ...
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(Springer, 2024-02)In a rare case, a 70-year-old female with polycythemia vera developed late-onset melanonychia, a seldom-documented side effect of hydroxyurea. Typically, melanonychia emerges within months of treatment, but this case is ...
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(Health and Medical Publishing Group, 2011-09)A 5-month-old South African girl presented to a casualty department with a short history of fever. General examination did not reveal organomegaly or neck stiffness. In keeping with local guidelines, malaria was excluded ...
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(MDPI Publishing, 2018-04-11)Pneumolysin (PLY), a member of the family of Gram-positive bacterial, cholesterol-dependent, -barrel pore-forming cytolysins, is the major protein virulence factor of the dangerous respiratory pathogen, Streptococcus ...
Now showing items 1-20 of 26