Successful treatment of disabling paroxysmal nonkinesigenic dyskinesia with deep brain stimulation of the globus pallidus internus
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| dc.contributor.author | Van Coller, Riaan
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| dc.contributor.author | Slabbert, Pieter
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| dc.contributor.author | Schutte, Clara-Maria
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| dc.date.accessioned | 2015-08-19T06:11:34Z | |
| dc.date.available | 2015-08-19T06:11:34Z | |
| dc.date.issued | 2014-10 | |
| dc.description.abstract | Paroxysmal nonkinesigenic dyskinesia (PNKD) causes episodes of treatment-resistant involuntary movements. Previous case reports showed effective treatment of PNKD with deep brain stimulation (DBS). We report 2 patients in whom DBS was highly successful when other treatment modalities had failed. METHODS : Two patients aged 34 and 24 years with a longstanding history of PNKD were treated with globus pallidus internus (GPi) DBS. Motor effects were monitored and followed up postoperatively and again at 6 months after surgery. RESULTS : Both patients responded very well to GPi DBS with complete suppression of dyskinesia after surgery in 1 patient and in the second after an additional adjustment of stimulation. CONCLUSION : GPi DBS might be an effective alternative treatment modality for PNKD | en_ZA |
| dc.description.librarian | hb2015 | en_ZA |
| dc.description.uri | http://www.karger.com/Journal/Home/224132 | en_ZA |
| dc.identifier.citation | Van Coller, R, Slabbert, P, Vaidyanathan, J & Schutte, C 2014, 'Successful treatment of disabling paroxysmal nonkinesigenic dyskinesia with deep brain stimulation of the globus pallidus internus', Stereotactic and Functional Neurosurgery, vol. 92, no. 6, pp. 388-392. | en_ZA |
| dc.identifier.issn | 1011-6125 (print) | |
| dc.identifier.issn | 1423-0372 (online) | |
| dc.identifier.other | 10.1159/000365226 | |
| dc.identifier.uri | http://hdl.handle.net/2263/49377 | |
| dc.language.iso | en | en_ZA |
| dc.publisher | Karger | en_ZA |
| dc.rights | © 2014 S. Karger AG, Basel | en_ZA |
| dc.subject | Paroxysmal dyskinesia | en_ZA |
| dc.subject | Paroxysmal nonkinesigenic dyskinesia (PNKD) | en_ZA |
| dc.subject | Deep brain stimulation (DBS) | en_ZA |
| dc.subject | Globus pallidus internus (GPi) | en_ZA |
| dc.title | Successful treatment of disabling paroxysmal nonkinesigenic dyskinesia with deep brain stimulation of the globus pallidus internus | en_ZA |
| dc.type | Postprint Article | en_ZA |
