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Browsing Research Articles (Neurology) by Title
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Soma, Prashilla; Ueckermann, Veronica; Sasikumar, S.S. (Sunayana); Mashoeshoe, K.S. (Sam)
(Elsevier, 2016-01)
The diagnosis of porphyria remains challenging as the condition is characterized by a myriad of clinical and biochemical features. More importantly, an acute attack is associated with increased morbidity and mortality. ...
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Hiesgen, Juliane; Annor, T.N.
(Health and Medical Publishing Group, 2023-01)
Posterior reversible encephalopathy syndrome (PRES) is an uncommon, subacute neurological disorder that presents radiologically with
a pattern of bilateral parieto-occipital areas of vasogenic oedema. Conditions commonly ...
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Chaudhuri, K.Ray; Podlewska, A.; Lau, Yue Hui; Gonde, C.; McIntosh, A.; Qamar, M.A.; O’Donoghue, S.; Larcombe, K.; Adeeko, M.; Gupta, A.; Bajwah, S.; Lafond, S.; Awogbemila, O.; Van Coller, Riaan; Murtagh, A.M.; Ocloo, J.E.
(Elsevier, 2023-12)
OBJECTIVES : Ethnic minorities (EM) are still underrepresented in research recruitment. Despite wide literature
outlining the barriers, enablers and recommendations for driving inclusion and diversity in research, there ...
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Schutte, Clara-Maria; Ranchhod, N.; Kakaza, Mandisa; Pillay, M.
(Health and Medical Publishing Group, 2013-06)
INTRODUCTION AND OBJECTIVES: Progressive multifocal leukoencephalopathy (PML), caused by the John Cunningham (JC) virus, results from lytic infection of predominantly oligodendrocytes. Following the HIV pandemic, the ...
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Schutte, Clara-Maria
(Health and Medical Publishing Group, 2013-11)
BACKGROUND. South Africa (SA) has a high prevalence of HIV infection with almost 11% of the population aged >2 years living with HIV. At the Steve Biko Academic Hospital, Pretoria, the Neurology Department has seen a steady ...
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Narotam-Jeena, Heena; Guttman, Mark; Van Hillegondsberg, Ludo; Van Coller, Riaan; Krause, Amanda; Carr, Jonathan
(Wiley, 2024-07)
BACKGROUND : Huntington disease-like 2 (HDL2) is a neurodegenerative disorder, affecting only individuals of African ancestry. Full penetrance occurs in individuals with 40 repeats or more. OBJECTIVE : To describe the ...
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Hiesgen, Juliane; Schutte, Clara-Maria
(South African Medical Association, 2023-03)
Since the identification of anti-N-methyl-D-aspartate (NMDA) receptor antibodies about 15 years ago, many patients with rapidly
progressing psychiatric symptoms, abnormal movements, seizures or unexplained coma have been ...
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Hiesgen, J.; Schutte, Clara-Maria
(South African Medical Association, 2023-04)
Autoimmune encephalitis (AE) represents a growing number of severe autoimmune-inflammatory diseases affecting both the white and
grey matter of the brain. In part 1 of this series, we focused on the epidemiology, ...
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Van Coller, Riaan; Van Rensburg, Elna; Schutte, Clara-Maria; Brink, Delene; Welthagen, Gerhard Frederick; Dove, Mike G.
(South African Medical Association, 2007-04)
Two patients with African sleeping sickness (SS) presented to
the neurology unit, Pretoria Academic Hospital, during 2004
and 2005. SS has shown a recent resurgence, with epidemics in
the Sudan, Angola and the Democratic ...
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Basson, Dion; Schutte, Clara-Maria; Van Coller, Riaan; Gould, Trevor
(Wits University Press, 2024-07-08)
BACKGROUND: Epidemiological data on brain tumours provides valuable insight into risk factors, treatment modalities and prognoses of these tumours. Despite abundant epidemiological data from brain tumour registries in ...
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Retief, Chris; Schutte, Clara-Maria; Baker, Malcolm Kevin
(Health and Medical Publishing Group, 2009-06)
BACKGROUND: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leuco-encephalopathy (CADASIL) is a hereditary autosomal dominant non-atherosclerotic nonamyloid cerebral arteriopathy. The disease was ...
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Mahne, A.C.; Carr, J.A.; Bardien, S.; Schutte, Clara-Maria
(Health and Medical Publishing Group, 2016-06)
BACKGROUND. Parkinson’s disease (PD), with a prevalence of up to 4% in Western countries, appears to be less common in Africa, possibly
in part because of genetic factors. African studies investigating the genetic causation ...
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Schutte, Clara-Maria; Townsend, T.; Van Coller, Riaan; Olorunju, Steve A.S.
(Health and Medical Publishing Group, 2013-01)
BACKGROUND. HTLV-1 associated myelopathy (HAM), or tropical spastic paraparesis, is caused by a retrovirus, the human T-cell
lymphotropic virus (HTLV). Although patients with HAM and HIV infection have been described, to ...
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Hiesgen, Juliane; Schutte, Clara-Maria; Olorunju, S.; Retief, J.
(Sage, 2017-06)
AIM : This retrospective cohort study analyzes the impact of possible risk factors on the survival chance of patients with cryptococcal meningitis. These factors include the patient's socio-economic background, age, gender, ...
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Pretorius, Etheresia; Swanepoel, A.C. (Albe Carina); Oberholzer, Hester Magdalena; Van der Spuy, Wendy Jeannette; Duim, Wiebren; Wessels, Pieter Frederik
(Springer, 2011-05)
Stroke is one of the leading causes of death worldwide. Formation of a fibrin clot is controlled by a group of tightly regulated plasma proteases and cofactors and a change in the fibrin fiber formation causes an alteration ...
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Schutte, Clara-Maria; Tsikane, Mukhethwa; Nchoe, Keorapetse
(AOSIS, 2021-05-27)
BACKGROUND: The Folstein mini mental state exam (MMSE) is the most commonly administered assessment of cognitive functioning; however, its utility in illiterate individuals is limited. In South Africa, more than eight ...
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Kisten, Ravendran; Van Coller, Riaan; Cassimjee, Nafisa; Lubbe, Elsabeth (Elsa); Vaidyanathan, Janardan; Slabbert, Pieter; Enslin, Nico; Schutte, Clara-Maria
(Elsevier, 2022)
INTRODUCTION : Although refractory Tourette Syndrome (TS) is rare, it poses great challenges in clinical practice. Co-morbid psychiatric symptoms often occur, negatively impacting quality of life. Deep brain stimulation ...
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Bhagwan, Bhavin; Pillay, Manesh; Schutte, Clara-Maria; Masenge, Andries; Kakaza, Mandisa
(Wits University Press, 2024-07-08)
BACKGROUND: Cerebral venous thrombosis (CVT) is an uncommon disorder accounting for approximately 1% of strokes worldwide There is a paucity of data regarding the association between an elevated factor VIII level and ...
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Pretorius, Etheresia; Swanepoel, A.C. (Albe Carina); Buys, A.V. (Antonia Vergina); Vermeulen, Natasha; Duim, Wiebren; Kell, Douglas B.
(Impact Journals, 2014-10)
A major trend in recent Parkinson’s disease (PD) research is the investigation of biological markers that could
help in identifying at‐risk individuals or to track disease progression and response to therapies. Central ...
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Stubgen, Joerg-Patrick
(Springer, 2008)
Facioscapulohumeral muscular dystrophy (FSHD) is not a recognized neuromuscular cause of dysphagia. However, a study of pharyngoesophageal function in FSHD has not been performed or reported. The aim of this study was to ...