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Browsing Theses and Dissertations (Haematology) by Issue Date

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Browsing Theses and Dissertations (Haematology) by Issue Date

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Detection of the calreticulin type 1 and type 2 mutations in a group of myeloproliferative neoplasm patients using molecular methods

Du Toit, Louise de Villiers (University of Pretoria, 2016)

The myeloproliferative neoplasms (MPN), formerly referred to as chronic myeloproliferative disorders, are a group of haematopoietic stem cell disorders that are characterized by clonal proliferation of one or more mature ...
Detection of the Janus kinase 2 V617F mutation using molecular methods

Senamela, Tshiphiri (University of Pretoria, 2016)

In 2005, a mutation located at exon 14 of the Janus Kinase gene on chromosome 9 was discovered in patients with Polycythaenia vera (PV), essential thrombocythaemia (ET) and primary myelofibrosis (PMF). The mutation (JAK2 ...

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