Cyclooxygenase inhibitors and the exercise-induced stress response

Claassen, Nico; Snyman, Jacques Rene; Koorts, Alida Maria; Nolte, Heinrich Wilhelm; Wagenaar, B.; Kruger, Mariana; Becker, Piet J.; Viljoen, Margaretha

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Cyclooxygenase inhibitors and the exercise-induced stress response

Claassen, Nico; Snyman, Jacques Rene; Koorts, Alida Maria; Nolte, Heinrich Wilhelm; Wagenaar, B.; Kruger, Mariana; Becker, Piet J.; Viljoen, Margaretha

URI: http://hdl.handle.net/2263/3708

Date: 2006-03

Abstract:

OBJECTIVE: This study investigated the effects of single dosages of the non-steroidal anti-inflammatory drug (NSAID) naproxen, and of the coxib, rofecoxib, on the exercise-induced stress response. Conclusion. The results of this study suggest a role for cyclooxygenase-1 (COX-1) in the exercise-induced cortisol and temperature response to exercise.

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