Glycation of fibrinogen in uncontrolled diabetic patients and the effects of glycaemic control on fibrinogen glycation

Pieters, Marlien; Van Zyl, Danie G.; Rheeder, Paul; Jerling, Johann C.; Loots, Du Toit; Van der Westhuizen, Francois Hendrikus; Gottsche, Louise T.; Weisel, John W.

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Glycation of fibrinogen in uncontrolled diabetic patients and the effects of glycaemic control on fibrinogen glycation

Pieters, Marlien; Van Zyl, Danie G.; Rheeder, Paul; Jerling, Johann C.; Loots, Du Toit; Van der Westhuizen, Francois Hendrikus; Gottsche, Louise T.; Weisel, John W.

URI: http://hdl.handle.net/2263/3295

Date: 2007

Abstract:

Evidence exists for a relationship between glycaemic control and macrovascular disease. Non-enzymatic glycation of proteins may explain this relationship in part. We investigated the effect of blood glucose control, under out-patient conditions, on fibrinogen glycation as well as the relationship between glycated fibrinogen and glycaemic control using a new sensitive method for the measurement of glycated fibrinogen.

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