• Pro-inflammatory interactions of streptolysin O toxin with human neutrophils in vitro 

  Joseph, Darren; Theron, Annette J.; Feldman, C.; Anderson, Ronald; Tintinger, Gregory (Taylor and Francis Group, 2024-12)

  The recent global resurgence of severe infections caused by the Group A streptococcus (GAS) pathogen, Streptococcus pyogenes, has focused attention on this microbial pathogen, which produces an array of virulence factors, ...
• Relationship between glycaemic control and the severity of erectile dysfunction in men with diabetes attending the diabetic clinic at Kalafong Provincial Tertiary Hospital 

  Mathekga, K.H.; Van Zyl, Danie G.; Hanekom, S. (Taylor and Francis, 2024-07)

  INTRODUCTION : Erectile dysfunction (ED) is common in men who are in their sixth decade of life and older, particularly those with diabetes. This study aimed to determine whether long-term glycaemic control affects the ...
• Cigarette smoking as a risk factor for Tuberculosis in adults : epidemiology and aspects of disease pathogenesis 

  Feldman, Charles; Theron, Annette J.; Cholo, Moloko C.; Anderson, Ronald (MDPI, 2024-02)

  It has been noted by the World Health Organisation that cases of tuberculosis in 2022 globally numbered 10.6 million, resulting in 1.3 million deaths, such that TB is one of the infectious diseases causing the greatest ...
• Persistently elevated expression of systemic, soluble co-inhibitory immune checkpoint molecules in people living with HIV before and one year after antiretroviral therapy 

  Labuschagne Naidoo, Robyn-Brooke; Steel, Helen C.; Theron, Annette J.; Anderson, Ronald; Tintinger, Gregory Ronald; Rossouw, Theresa M. (MDPI, 2024-06)

  Please read abstract in article.
• Who is to blame for the 'problem' of teenage pregnancy? Narratives of blame in two South African communities 

  Duby, Zoe; Bunce, Brittany; Fowler, Chantal; Bergh, Kate; Jonas, Kim; Slingers, Nevilene; Mathews, Catherine; Abdullah, Fareed (BMC, 2025-02)

  BACKGROUND : The framing of teenage pregnancy in social discourse influences the way in which adolescent girls and young women (AGYW) are treated, the extent to which they are supported, and to which they are able to engage ...
• Sodium, potassium-adenosine triphosphatase as a potential target of the anti-tuberculosis agents, clofazimine and bedaquiline 

  Mmakola, Khomotso Madimetsa Shelboy; Balmith, Marissa [; Steel, Helen C.; Said, Mohamed; Potjo, Moliehi; Van der Mescht, Mieke Adri; Hlatshwayo, Nomsa; Meyer, Pieter Willem Adriaan; Tintinger, Gregory Ronald; Anderson, Ronald; Cholo, Moloko C. (MDPI, 2024-12-04)

  Multidrug-resistant tuberculosis (MDR-TB) patients are treated with a standardised, short World Health Organization (WHO) regimen which includes clofazimine (CFZ) and bedaquiline (BDQ) antibiotics. These two antibiotics ...
• T-cell phenotypes and systemic cytokine profiles of people living with HIV admitted to hospital with COVID-19 

  Van der Mescht, Mieke Adri; Steel, Helen C.; De Beer, Zelda; Masenge, Andries; Abdullah, Fareed; Ueckermann, Veronica; Anderson, Ronald; Rossouw, Theresa M. (MDPI, 2024-11)

  Whether SARS-CoV-2 infection leads to a higher mortality and morbidity in people living with HIV (PLWH) in Africa remains inconclusive. In this study, we explored the differences in the T-cell phenotypes between people ...
• Individualized nutritional therapy in a patient with chronic critical illness 

  Ueckermann, Veronica; Francis, Engela (Elsevier, 2024-12)

  No abstract available.
• The evolving science on sudden cardiac death—the marriage of left ventricular hypertrophy and QT-dispersion 

  Ker, James A. (Wiley, 2024-11)

  The first description of sudden cardiac death was made by Hippocrates in the 4‘th century BC1. Such cases of sudden collapse and death has intrigued both the public and medical science for centuries and a practical ...
• I will find the best method that will work for me : navigating contraceptive journeys amongst South African adolescent girls and young women 

  Duby, Zoe; Bergh, Kate; Bunce, Brittany; Jonas, Kim; Slingers, Nevilene; Mathews, Catherine; Abdullah, Fareed (BioMed Central, 2024-08)

  BACKGROUND: Given that South Africa has one of the highest rates of pregnancy amongst adolescent girls and young women (AGYW) globally, the provision of contraceptives to this group has been a key focus in recent ...
• Mystical myositis : a case series from Kalafong Provincial Tertiary Hospital, Pretoria, South Africa 

  Myburgh, Michael (Wiley, 2024-08)

  Idiopathic inflammatory myositis (IIM) is an expanding field in rheumatology as more myositis-specific antibodies (MSAs) and myositis-associated antibodies (MAAs) become available for testing. Clinical signs and specific ...
• Angiogenesis and pancreatic cancer : novel approaches to overcome treatment resistance 

  Grobbelaar, C.W. (Craig); Kgomo, Mpho K.; Mabeta, Peaceful Lucy (Bentham Science Publishers, 2024-01)

  Pancreatic cancer (PCa) is acknowledged as a significant contributor to global cancer- related mortality and is widely recognized as one of the most challenging malignant diseases to treat. Pancreatic ductal adenocarcinoma ...
• Anti-melanoma differentiation associated gene 5 (MDA 5) dermatomyositis complicated by spontaneous pneumomediastinum : a case report from South Africa 

  Myburgh, Michael (Wiley, 2024-11)

  Spontaneous pneumomediastinum is a rare complication in anti–melanoma differentiation associated gene 5 (MDA 5) dermatomyositis (DM). In this case, it occurred relatively early in the course of this patient's illness before ...
• Landscape of esophageal cancer in Northern Kenya : experience from Garissa Regional Cancer Center 

  Abdihamid, Omar; Abdourahman, Houda; Ibrahim, Abdulsadiq; Kareu, Thinwa; Hadi, Abdullahi; Omar, Abeid; Mutebi, Miriam (eCancer Global Foundation, 2024-04)

  INTRODUCTION : Esophageal cancer (EC) is the ninth most common cancer and the sixth leading cause of cancer deaths worldwide. More than 80% of cases and deaths from EC occur within developing countries. In Kenya, cancer ...
• Feasibility of provision and vaccine hesitancy at a central hospital COVID-19 vaccination site in South Africa after four waves of the pandemic 

  Nair, Shanal; Tshabalala, Khanyisile; Slingers, Nevilene; Vanleeuw, Lieve; Basu, Debashis; Abdullah, Fareed (MDPI, 2024-06)

  BACKGROUND : As mortality declined significantly during the fourth and fifth waves compared to previous waves, the question of the future role of COVID-19 vaccination arose among both experts and the public in South Africa. ...
• The association of smoking and alcohol in colorectal cancer in black patients - case-control study 

  Kgomo, Mpho K.; Zingoni, Ratidzo L.; Becker, Piet J. (AOSIS, 2024-10)

  BACKGROUND : Studies have focused on smoking and alcohol as risk factors for colorectal cancer (CRC). Caucasians and other populations have been studied worldwide, and both smoking and alcohol have been validated as ...
• Cannabinoid hyperemesis syndrome 

  Elnagar, Ali; Kgomo, Mpho K.; Mokone, Modise; Yousif, Badreldin (BMJ Publishing Group, 2024-04)

  Cannabis use is legalised in many countries. We present a patient in their 40s who complained of recurrent abdominal pain and associated nausea and vomiting. The patient was previously seen in various hospitals, treated ...
• Epidemiology and aetiology of moderate to severe diarrhoea in hospitalised patients ≥5 years old living with HIV in South Africa, 2018- 2021 : a case-control analysis 

  Johnstone, Siobhan; Erasmus, Linda; Thomas, Juno; Groome, Michelle J.; Du Plessis, Nicolette Marie; Avenant, Theunis Johannes; De Villiers, Maryke; Page, N.A. (Nicola) (Public Library of Science, 2023-09-08)

  Diarrhoea is a recognised complication of HIV-infection, yet there are limited local aetiological data in this high-risk group. These data are important for informing public health interventions and updating diagnostic ...
• Adults living with type 2 diabetes experiences of a randomised adapted diabetes nutrition education programme : a qualitative process evaluation 

  Muchiri, Jane Wanjiku; Gericke, Gerda J.; Rheeder, Paul (NISC (Pty) Ltd and Informa UK Limited (trading as the Taylor & Francis Group), 2024)

  AIM : The purpose of this study was to investigate how a randomised controlled trial (RCT) of an adapted diabetes nutrition education programme (NEP) was received by adults with sub-optimally controlled (HbA1c of ≥ 8%) ...
• SARS-CoV-2 BA.4/5 infection triggers more cross-reactive FcγRIIIa signaling and neutralization than BA.1, in the context of hybrid immunity 

  Richardson, Simone I.; Mzindle, Nonkululeko; Motlou, Thopisang; Manamela, Nelia; Van der Mescht, Mieke Adri; Lambson, Bronwen E.; Everatt, Josie; Amoako, Daniel Gyamfi; Balla, Sashkia; Von Gottberg, Anne; Wolter, Nicole; De Beer, Zelda; De Villiers, Talita Roma; Bodenstein, Annie; Van den Berg, Gretha; Abdullah, Fareed; Rossouw, Theresa M.; Boswell, M.T.; Ueckermann, Veronica; Bhiman, Jinal N.; Moore, Penny L. (American Society for Microbiology, 2024-07)

  SARS-CoV-2 variants of concern (VOCs) differentially trigger neutralizing and antibody-dependent cellular cytotoxic (ADCC) antibodies with variable cross-reactivity. Omicron BA.4/5 was approved for inclusion in bivalent ...

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