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Theses and Dissertations (Medical Microbiology): Recent submissions
Now showing items 1-20 of 32
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(University of Pretoria, 2023-11)Antimicrobial resistance (AMR) due to Enterobacterales is a worldwide public health threat. The continuous emergence of multidrug resistant (MDR) bacteria in developing countries with poor sanitation programmes, inactive ...
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(University of Pretoria, 2023-12)Globally, antimicrobial resistance (AMR) in foodborne pathogenic bacteria of the family Enterobacteriaceae has continued to rise. There is an increase in public health concerns about the spread of multi-drug resistant (MDR) ...
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(University of Pretoria, 2023-11-03)Vulvovaginal candidiasis (VVC) is a common condition in women of childbearing age worldwide and usually presents as vaginal discharge syndrome (VDS). Other important causes of VDS are bacterial vaginosis (BV) and sexually ...
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(University of Pretoria, 2023)Antimicrobial resistance in Mycobacterium tuberculosis and Neisseria gonorrhoeae is emerging globally. Due to the limited treatment options, the World Health Organization has designated M. tuberculosis and N. gonorrhoeae ...
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(University of Pretoria, 2023)An increasing number of linezolid resistant (LZR), multidrug-resistant (MDR) Staphylococcus capitis infections have been observed in private hospitals in the greater Gauteng area since 2014. The aim of this study was to ...
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(University of Pretoria, 2015)Genetic typing of Klebsiella pneumoniae is used for epidemiological referencing. In the clinical setting it can be useful in outbreak investigations, understanding transmission and managing hospital infections. Multi-drug ...
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(University of Pretoria, 2020)Introduction: Carbapenems and colistin are the last-line antibiotics for treating Gram-negative bacterial infections. However, increasing reports of resistance to these antibiotics is being reported in clinical settings, ...
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(University of Pretoria, 2020)Background: Isoniazid (INH) is one of the most potent anti-tuberculosis (TB) drugs and a key component of the multi-drug regimen for the treatment of TB. Tuberculosis cases with initial INH resistance are more at risk ...
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(University of Pretoria, 2020)Tuberculosis (TB) is one of the top ten leading causes of death worldwide with millions of new TB cases reported every year. Understanding the genetic diversity of Mycobacterium tuberculosis (M. tuberculosis) is very ...
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(University of Pretoria, 2019)future, more robust or higher-resolution genomic typing tools, such as target Next Generation Sequencing (t-NGS) or metagenomic analysis are recommended to improve our understanding of the complexity of infections and for ...
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(University of Pretoria, 2014)Bacterial vaginosis (BV) and genital mycoplasmas are infections of the reproductive tract that play important roles in maternal and foetal health. Genital mycoplasmas include Mycoplasma genitalium, M. hominis, Ureaplasma ...
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(University of Pretoria, 2014)Staphylococcus aureus (S. aureus) is one of the leading causes of human diseases in hospital and community settings. Methicillin resistant Staphylococcus aureus (MRSA) has emerged as a significant problem worldwide, resisting ...
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(University of Pretoria, 2017)Sexually transmitted infections (STIs) continue to be a significant public health problem with an increased burden on women of reproductive age. These infections can be transmitted between humans by means of sexual ...
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(University of Pretoria, 2016)Background. In recent years, there has been an alarming increase in cases of multidrug-resistant tuberculosis (MDR-TB), and also extensively drug-resistant tuberculosis (XDR-TB). The emergence of these forms of tuberculosis ...
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(University of Pretoria, 2015)Tuberculosis (TB) is a major cause of death worldwide, especially in Asia and Africa. Genotyping methods such as insertion sequence 6110-restriction fragment length polymorphism (IS6110-RFLP), spoligotyping and mycobacterial ...
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(University of Pretoria, 2016)Polymyxins have previously been described to have activity against M. tuberculosis (M. tb), but further research was abandoned due to systemic toxicity concerns to achieve the required MIC. Colistin methanesulfonate (CMS), ...
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(University of Pretoria, 2015)The global control of tuberculosis (TB) is currently hindered by the low sensitivity of microscopy and the prolonged time-to-result of culture. Recent technical progress has improved both diagnostic accuracy and turnaround, ...
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(University of Pretoria, 2015)
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(University of Pretoria, 2014)Tuberculosis (TB) remains a major global health problem. In 2012, an estimated 8.6 million people developed TB and 1.3 million died from the disease (including 320 000 deaths among HIV-positive people). All countries are ...
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(University of Pretoria, 2013)Antifungal drug resistance is a growing problem. Several mechanisms contribute to the development of resistance to antifungal agents. In South Africa, little is known about the antifungal susceptibility of local yeast ...
Now showing items 1-20 of 32