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Browsing Theses and Dissertations (Immunology) by Title
Now showing items 1-20 of 62
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(University of Pretoria, 2011)Infection with the human immunodeficiency virus (HIV) constitutes a global pandemic, and South Africa forms part of the region known to house over two-thirds of HIV infected individuals worldwide. In the early stages of ...
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(University of Pretoria, 2007-01-05)Please read the abstract in the section 00front of this document
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(University of Pretoria, 2014)Background: Cancer is a crippling disease affecting 32.6 million people globally. It is currently ranked as the leading cause of death worldwide, and is associated with significant morbidity and mortality. Despite advances ...
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Bacterial translocation : cause of activated intestinal macrophages in decompensated liver disease (University of Pretoria, 2011)Background and Aim: Bacterial infections are a well described complication of cirrhosis and occur in 37% of hospitalized patients. Culture positive infections in addition to the presence of bacterial products and DNA ...
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(University of Pretoria, 2019)Human adipose-derived stromal cells (hASCs) have gained increasing attention in the past decade as a potential cell therapeutic product. hASCs are classified as multipotent, fibroblast-like, plastic-adherent cells that can ...
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(University of Pretoria, 2024-06)Umbilical cord blood (UCB) has been used for approximately 30 years as a source of haematopoietic stem and progenitor cells (HSPCs) for haematopoietic stem cell transplantation (HSCT). Advantages include less stringent ...
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(University of Pretoria, 2011-10-21)Rheumatoid arthritis (RA) is a chronic inflammatory disorder that has a predilection for peripheral synovial joints. The aetiology of the disease is not known, but current evidence indicates that multiple exogenous factors, ...
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(University of Pretoria, 2010-07-14)Infections remain the major cause of serious complications in cancer patients. Cancer patients receiving chemotherapy often develop febrile neutropenia and are at high risk for development of bacterial or fungal infections, ...
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(University of Pretoria, 2009-05-26)The one-way mixed lymphocyte culture (MLC) is used to assess histocompatibility between donor and recipient. First introduced in 1966, this method involves the co-culture of lymphocytes from the peripheral blood of the ...
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(University of Pretoria, 2014)Background: Due to its continuous exposure to food antigens and microbes, the gastrointestinal tract (GIT) is in a constant state of low level immune activation and contains an abundance of activated CCR5+CD4+ T lymphocytes, ...
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(University of Pretoria, 2022)The aim of this project was to develop assays that will allow for high-throughput screening to monitor adipogenesis. Such an assay may be useful for the identification of potential drug targets during the process of ...
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(University of Pretoria, 2023)The present study was undertaken with the initial objective of investigating the effects of six primary anti-pseudomonal antibiotics, namely amikacin, cefepime, ciprofloxacin, meropenem, piperacillin and tazobactam, on the ...
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(University of Pretoria, 2015)Introduction South Africa is ranked the third most obese country after the United States of America and Great Britain. According to a study conducted by the South African Medical Research Council, 61% of the South African ...
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(University of Pretoria, 2006-10-28)Please read the abstract in the section 00front of this document
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(University of Pretoria, 2016)Background: Neutrophil extracellular traps (NETs) constitute a network of chromatin fibres containing histone and antimicrobial peptides that are released by activated neutrophils. NETs protect the host against infection ...
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(University of Pretoria, 2019)Streptococcus pneumoniae (the pneumococcus) is a Gram-positive bacterium that frequently colonises the nasopharynx of healthy humans. In susceptible hosts, especially children under 5 years with underdeveloped immune systems ...
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(University of Pretoria, 2011)Streptococcus pneumoniae is a common human pathogen, causing severe and often life-threatening respiratory tract infections. Even though most patients receive appropriate antimicrobial chemotherapy, a significant percentage ...
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(University of Pretoria, 2013)Chemotherapy of tuberculosis (TB), a disease caused by Mycobacterium tuberculosis (M. tuberculosis), is successful against actively-growing bacilli but ineffective against dormant/persistent organisms, found mainly in a ...
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(University of Pretoria, 2005-09-22)The Streptococcus pneumoniae-derived toxin, pneumolysin, has been reported to augment neutrophil-mediated inflammatory responses in murine models of experimental infection of the airways, and to favour invasive pneumococcal ...
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(University of Pretoria, 2007-01-04)Please read the abstract in the section 00front of this document
Now showing items 1-20 of 62