Please note that UPSpace will be unavailable from Friday, 2 May at 18:00 (South African Time) until Sunday, 4 May at 20:00 due to scheduled system upgrades. We apologise for any inconvenience this may cause and appreciate your understanding.

Browsing Nuclear Medicine by Title

Now showing items 1-20 of 212

18F-FDG PET/CT as a noninvasive biomarker for assessing adequacy of treatment and predicting relapse in patients treated for pulmonary tuberculosis

Lawal, Ismaheel Opeyemi; Fourie, Bernard P.; Mathebula, Matsontso; Moagi, Ingrid; Lengana, Thabo; Moeketsi, Nontando; Nchabeleng, Maphoshane; Hatherill, Mark; Sathekge, Mike Machaba (Society of Nuclear Medicine, 2020-03)

Microbial culture is the gold standard for determining the effectiveness of tuberculosis treatment. End-of-treatment (EOT) 18F-FDG PET/CT findings are variable among patients with negative microbial culture results after ...
18F-FDG-PET/CT imaging of uterine cervical cancer recurrence in women with and without HIV infection

Lawal, Ismaheel Opeyemi; Ololade, Kehinde; Popoola, Gbenga O.; Ankrah, Alfred O.; Vorster, Mariza; Maes, Alex; Mokgoro, N.P. (Neo); Van de Wiele, Christophe; Sathekge, Mike Machaba (Edizioni Minerva Medica, 2022-03)

BACKGROUND : To compare the rate, time and, pattern of recurrence of cervical cancer between patients with and without HIV infection and to determine factors predicting cervical cancer recurrence in patients evaluated by ...
18F-PSMA-1007 in recurrent prostate cancer, a new frontier in prostate cancer PET imaging

Lengana, Thabo (University of Pretoria, 2020)

Prostate cancer remains a significant cause of cancer morbidity and mortality in men worldwide accounting for the second-highest incidence of all cancers in males. A disproportionate incidence, morbidity and mortality ...
[18F]F-poly(ADP-Ribose) polymerase inhibitor radiotracers for imaging PARP expression and their potential clinical applications in oncology

Ndlovu, Honest; Lawal, Ismaheel Opeyemi; Mdanda, Sipho; Kgatle, Mankgopo; Mokoala, K.M.G. (Kgomotso); Al-Ibraheem, Akram; Sathekge, Mike Machaba (MDPI, 2024-06-11)

Including poly(ADP-ribose) polymerase (PARP) inhibitors in managing patients with inoperable tumors has significantly improved outcomes. The PARP inhibitors hamper single-strand deoxyribonucleic acid (DNA) repair by ...
[18F]FDG PET and CT findings at therapy completion of pulmonary tuberculosis: comparison between HIV-positive and HIV-negative patients and impact on treatment response assessment

Ismaila, Aisha; Lawal, Ismaheel Opeyemi; Popoola, Gbenga O.; Mathebula, Matsontso; Moagi, Ingrid; Mokoala, Kgomotso M.G.; Honest, Ndlovu; Moeketsi, Nontando; Nchabeleng, Maphoshane; Hikuam, Chris; Hatherill, Mark; Fourie, P.B. (Petrus Bernardus); Sathekge, Mike Machaba (Springer, 2024-12)

BACKGROUND : [18F]FDG-PET/CT is a sensitive non-invasive tool for assessing treatment response in patients with pulmonary tuberculosis. The data on the performance of [18F]FDG-PET/CT for response assessment among patients ...
213Bi-PSMA-617 targeted alpha-radionuclide therapy in metastatic castration-resistant prostate cancer

Sathekge, Mike Machaba; Knoesen, Otto; Meckel, Marian; Modiselle, Moshe; Vorster, Mariza; Marx, Sebastian (Springer, 2017-06)

Prostate-specific membrane antigen radioligand therapy (PSMA-RLT) with 177Lu-PSMA holds great promise as a safe treatment option in patients with metastasized castration-resistant prostate cancer (mCRPC) with ...
225Ac-PSMA-617 in chemotherapy-naive patients with advanced prostate cancer : a pilot study

Sathekge, Mike Machaba; Bruchertseifer, Frank; Knoesen, Otto; Reyneke, Florette; Lawal, Ismaheel Opeyemi; Lengana, Thabo; Davis, Cindy; Mahapane, Johncy; Corbett, Ceceila; Vorster, Mariza; Morgenstern, Alfred (Springer, 2019-01)

BACKGROUND : A remarkable therapeutic efficacy has been demonstrated with 225Ac-prostate-specific membrane antigen (PSMA)- 617 in heavily pre-treated metastatic castration-resistant prostate cancer (mCRPC) patients.We ...
225Ac-PSMA-617 radioligand therapy of de novo metastatic hormone-sensitive prostate carcinoma (mHSPC): preliminary clinical findings

Sathekge, Mike Machaba; Bruchertseifer, Frank; Vorster, Mariza; Lawal, Ismaheel Opeyemi; Mokoala, Kgomotso M.G.; Reed, Janet D.; Maserumule, Letjie; Ndlovu, Honest; Hlongwa, Khanyi; Maes, Alex; Morgenstern, Alfred; Van de Wiele, Christophe (Springer, 2023-06)

PURPOSE : 225Ac-PSMA-617 has demonstrated good anti-tumor effect as a treatment option for metastatic castration-resistant prostate cancer (mCRPC) patients. No study has previously assessed treatment outcome and survival ...
[68 Ga]Ga-FAPI versus [18F]F-FDG in malignant melanoma: complementary or counterpoint?

Mokoala, Kgomotso M.G.; Emil, Novruzov; Lawal, Ismaheel Opeyemi; Antke, Christina; Giesel, Frederik L.; Sathekge, Mike Machaba (Springer, 2022-06)

No abstract available.
68Ga radiolabeling of NODASA-functionalized phage display-derived peptides for prospective assessment as Tuberculosis-specific PET radiotracers

Gouws, Christiaan A.; Naicker, Tricia; De la Torre, Beatriz G.; Albericio, Fernando; Duvenhage, Janie; Kruger, Hendrik G.; Marjanovic-Painter, Biljana; Mdanda, Sipho; Zeevaart, Jan Rijn; Ebenhan, Thomas; Govender, Thavendran (Wiley, 2024-09)

Please read abstract in article.
68Ga-FAPI-PET/CT in patients with various gynecological malignancies

Dendl, Katharina; Koerber, Stefan A.; Finck, Rebecca; Mokoala, Kgomotso M.G.; Staudinger, Fabian; Schillings, Lisa; Heger, Ulrike; Rohrich, Manuel; Kratochwil, Clemens; Sathekge, Mike Machaba; Jager, Dirk; Debus, Jurgen; Haberkorn, Uwe; Giesel, Frederik L. (Springer, 2021-11)

PURPOSE : 68Ga-FAPI (fibroblast activation protein inhibitor) is a novel and highly promising radiotracer for PET/CT imaging. The aim of this retrospective analysis is to explore the potential of FAPI-PET/CT in gynecological ...
68Ga-nitroimidazole PET/CT imaging of hypoxia in tuberculosis : a case series

Bresser, Philppa Lynn; Reed, Janet D.; Sathekge, Mike Machaba; Vorster, Mariza (Wiley Open Access, 2022-12)

Tuberculosis (TB) lesions in humans have been proven to be severely hypoxic with hypoxia leading to latency and dormancy of disease. Dormant TB lesions become less susceptible to standard TB treatment regimens with varying ...
68Ga-PSMA-11 PET/CT in primary staging of prostate carcinoma : preliminary results on differences between black and white South-Africans

Sathekge, Mike Machaba; Lengana, Thabo; Maes, Alex; Vorster, Mariza; Zeevaart, Jan Rijn; Lawal, Ismaheel Opeyemi; Ebenhan, Thomas; Van de Wiele, Christophe (Springer, 2018-02)

PURPOSE : The incidence of prostate cancer is 60% higher and the mortality rate is two- to three-times greater in black versus white men. We report on differences in 68Ga-PSMA-11 PET/CT imaging findings in 77 black ...
68Ga-PSMA-HBED-CC PET imaging in breast carcinoma patients

Sathekge, Mike Machaba; Lengana, Thabo; Modiselle, Moshe; Vorster, Mariza; Zeevaart, Jan Rijn; Maes, Alex; Ebenhan, Thomas; Van de Wiele, Christophe (Springer, 2017-04)

BACKGROUND : To report on imaging findings using 68Ga-PSMAHBED- CC PET in a series of 19 breast carcinoma patients. METHODS : 68Ga-PSMA-HBED-CC PET imaging results obtained were compared to routinely performed staging ...
[68Ga]Ga-NODAGAZOL uptake in atherosclerotic plaques correlates with the cardiovascular risk profile of patients

Ndlovu, Honest; Lawal, Ismaheel Opeyemi; Popoola, Gbenga O.; Brits, Bradley; Mokoala, Kgomotso M.G.; Maserumule, Letjie; Hlongwa, K.; Mahapane, Johncy; Davis, Cindy; Sathekge, Mike Machaba (Springer, 2022-07)

Please read abstract in the article.
[68ga]ga-pentixafor for pet imaging of vascular expression of cxcr-4 as a marker of arterial inflammation in hiv-infected patients : a comparison with18f[fdg] pet imaging

Lawal, Ismaheel Opeyemi; Popoola, Gbenga O.; Mahapane, Johncy; Kaufmann, Jens; Davis, Cindy; Ndlovu, Honest; Maserumule, Letjie C.; Mokoala, Kgomotso M.G.; Bouterfa, Hakim; Wester, Hans-Jurgen; Zeevaart, Jan Rijn; Sathekge, Mike Machaba (MDPI, 2020-12)

People living with human immunodeficiency virus (PLHIV) have excess risk of atherosclerotic cardiovascular disease (ASCVD). Arterial inflammation is the hallmark of atherogenesis and its complications. In this study we ...
89Zr-Leukocyte labelling for cell trafficking : in vitro and preclinical investigations

Kahts, Maryke; Guo, Hua; Kommidi, Harikrishna; Yang, Yanping; Sayman, Haluk Burcak; Summers, Beverley; Ting, Richard; Zeevaart, Jan Rijn; Sathekge, Mike Machaba; Aras, Omer (SpringerOpen, 2023-11-06)

BACKGROUND : The non-invasive imaging of leukocyte trafficking to assess inflammatory areas and monitor immunotherapy is currently generating great interest. There is a need to develop more robust cell labelling and ...
Aberrant vascular anatomy associated with artifactual focal avidity in the liver on PSMA PET

Lawal, Ismaheel Opeyemi; Pectasides, Melina; Parihar, Ashwin Singh; Shah, Hardik U.; Halkar, Raghuveer K.; Jani, Ashesh B.; Schuster, David M. (Lippincott Williams and Wilkins, 2023-09)

68Ga–prostate-specific membrane antigen (PSMA) PET/CT is a valuable tool for staging and restaging of prostate cancer. Prostate-specific membrane antigen expression is not specific to prostate cancer, as it is expressed ...
Accuracy of bone SPECT/CT for identifying hardware loosening in patients who underwent lumbar fusion with pedicle screws

Hudyana, Hendrah; Maes, Alex; Vandenberghe, Thierry; Fidlers, Luc; Sathekge, Mike Machaba; Nicolai, Daniel; Van de Wiele, Christophe (Springer, 2016-02)

BACKGROUND : The aim of this retrospective study was to evaluate the accuracy of bone SPECT (single photon emission computed tomography)/CT (computed tomography) in diagnosing loosening of fixation material in patients ...
Activity quantification and dosimetry in radiopharmaceutical therapy with reference to 177Lutetium

Ramonaheng, Keamogetswe; Qebetu, Milani; Ndlovu, Honest; Swanepoel, Cecile; Smith, Liani; Mdanda, Sipho; Mdlophane, Amanda; Sathekge, Mike Machaba (Frontiers Media, 2024-03)

Radiopharmaceutical therapy has been widely adopted owing primarily to the development of novel radiopharmaceuticals. To fully utilize the potential of these RPTs in the era of precision medicine, therapy must be optimized ...

Now showing items 1-20 of 212

Search UPSpace

Browse

All of UPSpace
This Community
- Issue Date
- Authors
- Titles
- Subjects
- Supervisor
- UP Author
- UP Postgraduate
- Type

Browsing Nuclear Medicine by Title

Browsing Nuclear Medicine by Title

Search UPSpace

Browse

All of UPSpace

This Community

My Account

UPSpace Workspace