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Browsing Research Articles (Physiology) by Type "Postprint Article"
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Visagie, M.H. (Michelle Helen); Birkholtz, Lyn-Marie; Joubert, Annie M.
(Wiley, 2014)
Microtubules are important targets when studying potential anticancer agents since disturbance of these microtubule dynamics results in cell cycle arrest and cell death. 2-Methoxyestradiol is a naturally occurring metabolite ...
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Visagie, M.H. (Michelle Helen); Joubert, Annie M.
(Springer, 2011-11)
In anticancer research where the focus is on
finding agents that induces cell death while leaving nontumorigenic
cells less affected, a novel 2-methoxyestradiol
derivative has come forth. 2-Methoxyestradiol-bis-sulfam ...
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Masingi, Ntsakisi I.; Laher, Zaheer; Pretorius, Etheresia
(Wiley, 2017-03)
A 60-year-old human immunodeficiency virus-positive woman presented with splenomegaly.
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Velleman, Mark D.; Jansen van Rensburg, Audrey; Janse van Rensburg, Dina Christina; Strauss, Org
(Edizione Minerva Medica, 2015-09)
A 28-year-old male rugby player presented with severe onset of right hip pain when he fell awkward after a ruck during an international match. A rare case of an acute strain of the obturator internus muscle, a deep muscle ...
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Janse van Rensburg, Maxine; Bester, Megan; Van Rooy, Mia-Jeanne; Oberholzer, Hester Magdalena
(Sage, 2023-08)
Cardiovascular diseases (CVD) are a common global cause of death and are therefore a major health concern. Inhaled or ingested environmental heavy metals contribute to the development of CVD. The aim of this study was to ...
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Draper, Maxine; Bester, Megan; Van Rooy, Mia-Jeanne; Oberholzer, Hester Magdalena
(Taylor and Francis, 2023)
Exposure to environmental metal pollutants is linked to oxidative stress and the subsequent development of neurological disease. In this study, the effects of copper, manganese, and mercury, were evaluated at X100 the World ...
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Draper, Maxine; Bester, Megan Jean; Van Rooy, Mia-Jeanne; Oberholzer, H.M.
(Routledge, 2023)
The rise in respiratory disease has been attributed to an increase in environmental pollution. Heavy metals contribute to environmental contamination via air, water, soil and food. The effects of atmospheric exposure to ...
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Mabeta, Peaceful Lucy; Pepper, Michael Sean
(Elsevier, 2015-02)
Herein, we describe the effects of Taxol on endothelioma cell growth and migration in vitro and on
vascular tumor growth in vivo. The effects of Taxol on endothelioma cell growth were determined using
the crystal violet ...
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Grobbelaar, C.W. (Craig); Kgomo, Mpho K.; Mabeta, Peaceful Lucy
(Bentham Science Publishers, 2024-01)
Pancreatic cancer (PCa) is acknowledged as a significant contributor to global cancer- related mortality and is widely recognized as one of the most challenging malignant diseases to treat. Pancreatic ductal adenocarcinoma ...
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Skermana, Nicola B.; Joubert, Annie M.; Cronje, Marianne J.
(Elsevier, 2011-10)
AIM OF STUDY: Oesophageal cancer is the ninth most common cancer in the world and the second most common cancer among South African men. It also has one of the lowest possibilities of cure, with the
5-year survival rate ...
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Repsold, Lisa; Pool, Roger; Karodia, Mohammed; Tintinger, Gregory Ronald; Becker, Piet J.; Joubert, Anna Margaretha
(Wiley, 2021-06)
Chronic myeloid leukaemia (CML) is a malignancy of the haematopoietic stem cells. The first line of treatment for CML, especially in developing countries, remains the first-generation tyrosine kinase inhibitor, Imatinib. ...
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Choudhary, Arbind Kumar
(Bentham Science, 2018)
BACKGROUND : Individuals with Type II Diabetes (T2D) have to manage blood glucose levels to sustain health and longevity. Artificial sweeteners (including aspartame) are suggested sugar alternatives for these individuals. ...
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Ngassa Piotie, Patrick; Wood, Paola Silvia; Muchiri, Jane Wanjiku; Webb, Elizabeth M.; Rheeder, Paul
(Elsevier, 2021-10)
AIMS : To investigate the attitudes and beliefs of primary healthcare practitioners (HCPs) towards initiating insulin therapy for people with type 2 diabetes (T2D) in South Africa.
METHODS : A cross-sectional survey was ...
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Negrao, Bianca Lee; Bipath, Priyesh; Van der Westhuizen, Deborah; Viljoen, Margaretha
(Karger, 2011-01)
OBJECTIVE: The aim of this study was to assess autonomic nervous system functioning in children with attention-deficit/hyperactivity disorder (ADHD) and to examine the effects of methylphenidate and focussed attention. ...
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Bayne, Helen; Albertus, Yumna; Breen, Sarah; Green, Andrew; De Andrade, Andre Gustavo; Kramer, Mark; Carpes, Felipe P.
(American Physiological Society, 2021-03)
The “Biomechanics without Borders: Teaching Biomechanics in Brazil and South Africa” involved academics from different countries combining efforts to improve remote education. In addition to the live discussions, the event ...
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Wolmarans, Elize; Boy, S.C. (Sonja); Nel, Sulette; Mercier, Anne Elisabeth; Pepper, Michael Sean
(Springer, 2017-11)
The recurrence and/or lack of response of certain tumors to radio- and chemotherapy has been attributed to a small subpopulation of cells termed cancer stem cells (CSCs). CSCs have been identified in many tumors (including ...
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Nielsen, Vance G.; Pretorius, Etheresia
(Elsevier, 2014-03)
Within the past decade there have been several investigations attempting to define the impact of exogenous and
endogenous carbon monoxide exposure on hemostasis. Critically, two bodies of literature have emerged, with
carbon ...
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Nielsen, Vance G.; Pretorius, Etheresia; Bester, Janette; Jacobsen, Wayne K.; Boyle, Patrick K.; Reinhard, Joao P.
(Bentham Science, 2015-01)
Alzheimer’s disease (AD) is a significant source of morbidity and mortality for millions of
people worldwide, and multiple potential etiologies have been postulated to contribute to AD. Among
these, spontaneous cerebral ...
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Donaldson, Byron J.; Bezodis, Neil; Bayne, Helen
(Routledge, 2023)
Identifying coordination strategies used by sprinters and features that differentiate these strategies will aid in understanding different technical approaches to initial sprint acceleration. Moreover, multiple effective ...
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Olumuyiwa-Akeredolu, Oore-ofe O.; Soma, Prashilla; Buys, A.V. (Antonia Vergina); Debusho, Legesse Kassa; Pretorius, Etheresia
(Elsevier, 2017-12)
The inflammatory burden of the complex rheumatoid arthritis (RA) disease affects several organ-systems, including rheological properties of blood and its formed elements. Red blood cells (RBCs) are constantly exposed to ...