Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes

Alcantara, Luiz Carlos Junior; De Oliveira, Tulio; Gordon, Michelle; Pybus, Oliver G.; Mascarenhas, Rita E.; Seixas, Magda O.; Gonçalves, Marilda; Hlela, Carol; Galvao-Castro, Bernardo; Cassol, Sharon

UPSpace Home
→
Health Sciences
→
Medical Virology
→
Media & Communication (Medical Virology)
→
View Item

Please note that UPSpace will be unavailable from Friday, 2 May at 18:00 (South African Time) until Sunday, 4 May at 20:00 due to scheduled system upgrades. We apologise for any inconvenience this may cause and appreciate your understanding.

Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes

Cassol, Sharon; Alcantara, Luiz Carlos Junior; De Oliveira, Tulio; Gordon, Michelle; Pybus, Oliver G.; Mascarenhas, Rita E.; Seixas, Magda O.; Gonçalves, Marilda; Hlela, Carol; Galvao-Castro, Bernardo

URI: http://hdl.handle.net/2263/3532

Date: 2006-03

Abstract:

We compared the genetic diversity of the Brazilian human T-cell lymphotropic virus type 1 isolates with those found in KwaZulu–Natal (KZN), South Africa, and with the genetic background of the hosts. The seroprevalence rate in KZN was 1.7%. All sequences belonged to the A subgroup. The presence of South African sequences in two different clusters from Brazil, and the finding of the bA-globin haplotype in infected hosts are consistent with the transmission of this virus from Southern Africa to Brazil.

Show full item record