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Browsing Anatomical Pathology by Type "Article"
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Louw, Melanie
(Health and Medical Publishing Group, 2012-02)
No abstract available.
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Eyal, Paula
(Health and Medical Publishing Group, 2012)
Barrett's oesophagus (BO) is defined as the occurrence of metaplastic, specialised columnar epithelium lining the distal part of the oesophagus. Evidence points to this as a metaplastic condition in reaction to ulceration ...
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Crause, Chantelle
(Health and Medical Publishing Group, 2015-01)
This case report highlights the importance of timely diagnosis of disseminated fungal infections in neonates, as well as the increased
incidence of infection with non-albicans Candida, and the association with surgical ...
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Karolak, Justyna A.; Gambin, Tomasz; Honey, Engela M.; Slavik, Tomas; Popek, Edwina; Stankiewicz, Paweł
(BioMed Central, 2020-03-06)
BACKGROUND : Application of whole genome sequencing (WGS) enables identification of non-coding variants that
play a phenotype-modifying role and are undetectable by exome sequencing. Recently, non-coding regulatory
single ...
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Joubert, Doret M.; Rossouw, Servaas Hofmeyr; Solomon, C.; Meyer, Pieter Willem Adriaan
(Health and Medical Publishing Group, 2022-11)
BACKGROUND. The anatomical pathology autopsy serves several purposes, notably as a quality management tool for evaluation of accuracy
in clinical diagnosis. Despite its value, for various reasons there has been an ...
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Carrim, Yacoob Omar; Gaxa, Luvo; Van der Schyff, Fransica; Bida, Nndweleni Meshack; Omar, Fareed E.; Lockhat, Zarina I.
(Elsevier, 2017-12)
Colorectal carcinoma in children and adolescents is extremely rare, with an annual incidence <0.3 cases
per million, most frequently reported in the second decade of life. It accounts for severe morbidity and
poor prognosis ...
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Muller, M.; Kalmeier, G.; Eyal, P.; De Bruin, A.; Pool, Roger; Du Rant, C.; Ehlers, Rene; Stander, Andre; Van Schoor, Albert-Neels; Nortje, Evangeline; Du Toit, Peet J.
(Health and Medical Publishing Group, 2017-09)
BACKGROUND. The number of peripheral blood and endometrial natural killer cells varies greatly during implantation and the first trimester of
pregnancy and is thought to play a role in the maintenance of a healthy pregnancy. ...
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Dlamini, Zodwa; Molefi, Thulo; Khanyile, Richard; Mkhabele, Mahlori; Damane, Botle Precious; Kokoua, Alexandre; Bida, Meshack; Saini, Kamal S.; Chauke-Malinga, Nkhensani; Luvhengo, Thifhelimbilu Emmanuel; Hull, Rodney
(Springer, 2024-03)
The formidable impact of breast cancer extends globally, with South Africa facing pronounced challenges, including significant disparities in breast cancer screening, treatment and survival along ethnic and socioeconomic ...
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Buffart, Tineke E.; Louw, Melanie; Van Grieken, Nicole C.T.; Tijssen, Marianne; Carvalho, Beatriz; Ylstra, Bauke; Grabsch, Heike; Mulder, Chris J.J.; Van de Velde, Cornelis J.H.; Van der Merwe, Schalk Willem; Meijer, Gerrit A.
(BioMed Central, 2011-01)
BACKROUND: Infection with H. pylori is important in the etiology of gastric cancer. Gastric cancer is infrequent in Africa, despite high frequencies of H. pylori infection, referred to as the African enigma. Variation in ...
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Heunis, Nanette; Horton, A.; Richter, Karin Louise; Dreyer, Greta; Louw, Melanie
(2014)
BACKGROUND: The L1 capsid protein is a viral nuclear protein that encapsidates the human papillomavirus (HPV) DNA to build
new infectious particles. Previous studies in immune-competent patients have shown that detectable ...
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Rad, Amir; Sorbye, Sveinung Wergeland; Dreyer, Greta; Hovland, Siri; Falang, Bente Marie; Louw, Melanie; Skjeldestad, Finn Egil
(Lippincott, Williams and Wilkins, 2017)
Accurate identification of human papillomavirus (HPV)-types in cervical cancer tissue may be important for tailoring tests for primary
screening and types to be included in a vaccine. The aim of this study was to compare ...
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Mbeje, Mandisa; Kandhavelu, Jeyalakshmi; Penny, Clement; Kgoebane-Maseko, Minah; Dlamini, Zodwa; Marima, Rahaba
(MDPI, 2023-09-01)
Prostate cancer (PCa) is the leading cancer in men globally. The association between PCa
and long non-coding RNAs (lncRNAs) has been reported. Aberrantly expressed lncRNAs have been
documented in each of the cancer ...
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Lerch, Julia M.; Pai, Rish K.; Brown, Ian; Gill, Anthony J.; Jain, Dhanpat; Kovari, Bence; Kushima, Ryoji; Sheahan, Kieran; Slavik, Tomas; Srivastava, Amitabh; Lauwers, Gregory Y.; Langner, Cord
(Springer, 2022-06)
The extent of gastric intestinal metaplasia (GIM) can be used to determine the risk of gastric cancer. Eleven international
gastrointestinal expert pathologists estimated the extent of GIM on haematoxylin and eosin (H&E)- ...
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Dinkel, Jurgen Erich
(Health and Medical Publishing Group, 2012-02)
Lymph node biopsy, if performed correctly, is likely to yield an optimal diagnostic result. However, in view of the invasive nature of the procedure, biopsy should only be undertaken in patients with a definitive clinical ...
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Jackson, Brandon Spencer; Pratt, T.L.; Van Rooyen, A.
(Health and Medical Publishing Group, 2017-04)
Mammary analogue secretory carcinoma (MASC) is a rare and recently described tumour of the salivary glands. MASC has similar
histomorphological and immunohistochemical features of secretory carcinoma of the breast. MASC ...
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Tenea, Daniela; Dinkel, Jurgen Erich; Becker, Jurgen C.; Van der Walt, Elizabeth
(Karger, 2019)
Merkel cell carcinoma (MCC) is a rare cutaneous neoplasm of presumed neuroendocrine origin, with aggressive behavior and poor prognosis, that tends to have an increased incidence among elderly Caucasians and immunosuppressed ...
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Baker, Gillian; Babb, Chantal; Schnugh, Desmond; Nayler, Simon; Melanie, Louw; Goedhals, Jacqueline; Bringuier, Pierre-Paul; Blay, Jean-Yves; Willem, Pascale
(Spandisos, 2013)
Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours of the digestive tract. Pathogenesis is linked to activating mutations identified in two proto-oncogenes, v-kit Hardy/Zuckerman 4 feline ...
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Ngcelwane, M.V. (Mthunzi); Omar, Shaheed V.; Said, H.M. (Halima Mohammed); Bida, Nndweleni Meshack
(Korean Society of Spine Surgery, 2023-06)
STUDY DESIGN : Prospective study.
PURPOSE : To evaluate the utility of whole genome sequencing (WGS) in drug resistance testing, lineage of the organisms, and organism-related factors responsible for bacilli settling in ...
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Alaouna, Mohammed; Penny, Clement; Hull, Rodney; Molefi, Thulo; Chauke-Malinga, Nkhensani; Khanyile, Richard; Makgoka, Malose; Bida, Meshack; Dlamini, Zodwa
(MDPI, 2023-06-16)
Triple negative breast cancer (TNBC) is a very aggressive subtype of breast cancer that
lacks estrogen, progesterone, and HER2 receptor expression. TNBC is thought to be produced by
Wnt, Notch, TGF-beta, and VEGF pathway ...
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Solomon, Christa; Louw, Melanie; Van Aardt, M.C. (Matthys Cornelis); Dreyer, Greta
(Medpharm Publications, NISC (Pty) Ltd and Informa UK Limited [trading as the Taylor & Francis Group], 2017)
BACKGROUND : Cervical carcinoma was the second leading malignancy in South African women (following breast carcinoma)
in 2010. This study aimed to correlate histopathological criteria and immunohistochemical stains in ...