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Browsing Immunology by Type "Thesis"
Now showing items 1-20 of 29
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(University of Pretoria, 2007-01-05)Please read the abstract in the section 00front of this document
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(University of Pretoria, 2019)Human adipose-derived stromal cells (hASCs) have gained increasing attention in the past decade as a potential cell therapeutic product. hASCs are classified as multipotent, fibroblast-like, plastic-adherent cells that can ...
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(University of Pretoria, 2024-06)Umbilical cord blood (UCB) has been used for approximately 30 years as a source of haematopoietic stem and progenitor cells (HSPCs) for haematopoietic stem cell transplantation (HSCT). Advantages include less stringent ...
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(University of Pretoria, 2011-10-21)Rheumatoid arthritis (RA) is a chronic inflammatory disorder that has a predilection for peripheral synovial joints. The aetiology of the disease is not known, but current evidence indicates that multiple exogenous factors, ...
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(University of Pretoria, 2014)Background: Due to its continuous exposure to food antigens and microbes, the gastrointestinal tract (GIT) is in a constant state of low level immune activation and contains an abundance of activated CCR5+CD4+ T lymphocytes, ...
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(University of Pretoria, 2006-10-28)Please read the abstract in the section 00front of this document
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(University of Pretoria, 2005-09-22)The Streptococcus pneumoniae-derived toxin, pneumolysin, has been reported to augment neutrophil-mediated inflammatory responses in murine models of experimental infection of the airways, and to favour invasive pneumococcal ...
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(University of Pretoria, 2007-01-04)Please read the abstract in the section 00front of this document
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(University of Pretoria, 2017)Patients with sepsis need to be distinguished from those with systemic inflammation due to non-infectious causes (SIRS) so that empiric antimicrobial therapy can be administered timeously to those with sepsis. The current ...
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(University of Pretoria, 2017)Gene therapy is a field in medical research that is being investigated for the treatment of genetic, non-communicable and infectious diseases. The results obtained from clinical trials that make use of gene therapy show ...
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(University of Pretoria, 2019-11-12)Prostate cancer (PC) is the second most commonly occurring cancer in men, and the fourth most common commonly occurring cancer overall. Almost all PC begins in an androgen-dependent state with androgen deprivation therapy ...
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(University of Pretoria, 2019)Umbilical cord blood (UCB) is a rich source of hematopoietic stem and progenitor cells (HSPCs). There are however limitations to using UCB as a regular source for hematopoietic stem cell transplantation (HSCT). The number ...
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(University of Pretoria, 2018)There is documented evidence of high genetic diversity amongst African populations, but there is limited data on human leukocyte antigen (HLA) diversity in these populations. HLA genes are highly polymorphic, and encode ...
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(University of Pretoria, 2007-01-04)The intra- and extracellular activities of 2 novel tetramethylpiperidine (TMP)-substituted phenazines, B4121 and B4128 against Mycobacterium tuberculosis H37R (ATCC 27294) were determined and compared with those of clofazimine ...
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(University of Pretoria, 2023)Breast cancer (BC) is the most prevalent cancer in females and the leading cause of cancer deaths. Treatment options include mastectomy, chemotherapy, and radiotherapy. While these treatments can improve 5-year survival ...
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(University of Pretoria, 2019)Adult mesenchymal stromal cells show promise therapeutically due to their multipotent differentiation capacity, immunomodulatory properties, paracrine signalling and ability to migrate to sites of injury. The potential use ...
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(University of Pretoria, 2011)Montelukast (ML) is primarily an antagonist of type 1 cysteinyl leukotriene receptors (CysLT1R), an activity which underpins its therapeutic efficacy in bronchial asthma. However, ML has also been reported to be useful in ...
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(University of Pretoria, 2008-05-30)Please read the abstract in the section 00front of this document
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(University of Pretoria, 2013)Manganese (Mn2+) is an essential nutrient required in trace amounts for human health; however excessive exposure to the metal, predominantly reported in adults exposed occupationally via inhalation, has been associated ...
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(University of Pretoria, 2010)The major cause of HIV-related mortality in Sub-Saharan countries is pulmonary tuberculosis (TB), which is an escalating threat due to the emergence of multidrug resistant (MDR) and extremely multidrug resistant (XDR) TB. ...
Now showing items 1-20 of 29