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- Browsing Research Articles (Biochemistry) by Issue Date
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Browsing Research Articles (Biochemistry) by Issue Date
Now showing items 1-20 of 666
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(BioMed Central, 2006-11)The organization and mining of malaria genomic and post-genomic data is important to significantly increase the knowledge of the biology of its causative agents, and is motivated, on a longer term, by the necessity to ...
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(Elsevier, 2007-02)Spermidine synthase is currently considered as a promising drug target in the malaria parasite, Plasmodium falciparum, due to the vital role of spermidine in the activation of the eukaryotic translation initiation factor ...
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(Elsevier, 2007-03-19)Mycolic acids (Scheme 1) are major constituents of the cell envelope of Mycobacterium tuberculosis and other mycobacteria, some of which are pathogenic to animals and humans.1 and 2 Their presence is thought to be linked ...
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(BioMed Central, 2007-05)BACKGROUND: The increasing emergence of Plasmodium falciparum parasites resistant to most of the cost-effective drugs has necessitated the identification of novel leads and drug targets. Parasitespecific inserts in enzymes ...
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(Elsevier, 2007-06-13)Sutherlandia frutescens is a well-known South African herbal remedy traditionally used for stomach problems, internal cancers, diabetes, various inflammatory conditions and recently to improve the overall health in cancer ...
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(South African Veterinary Association, 2007-12)The quality of induction of general anesthesia produced by ketamine and propofol, 2 of the most commonly used anaesthetic agents in cats, was assessed. Eighteen cats admitted for elective procedures were randomly assigned ...
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(Blackwell, 2008)Long genes should be rare in archaea and eubacteria because of the demanding costs of time and resources for protein production. The search in 580 sequenced prokaryotic genomes, however, revealed 0.2% of all genes to be ...
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(Blackwell, 2008)The global feature of the completely sequenced Alcanivorax borkumensis SK2 type strain chromosome is its symmetry and homogeneity. The origin and terminus of replication are located opposite to each other in the chromosome ...
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(BioMed Central, 2008)Malaria remains the world's most devastating tropical infectious disease with as many as 40% of the world population living in risk areas. The widespread resistance of Plasmodium parasites to the cost-effective chloroquine ...
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(BioMed Central, 2008)BACKGROUND: Microarray technology makes it possible to identify changes in gene expression of an organism, under various conditions. Data mining is thus essential for deducing significant biological information such as the ...
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(Academy of Science of South Africa, 2008)No abstract available
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(BioMed Central, 2008)BACKGROUND: Protein structure plays a pivotal role in elucidating mechanisms of parasite functioning and drug resistance. Moreover, protein structure aids the determination of protein function, which can together with the ...
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(Elsevier, 2008-02)Functional genomics approaches are indispensable tools in the drug discovery arena and have recently attained increased attention in antibacterial drug discovery research. However, the application of functional genomics ...
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(BioMed Central, 2009-07)BACKGROUND: Up to half a billion human clinical cases of malaria are reported each year, resulting in about 2.7 million deaths, most of which occur in sub-Saharan Africa. Due to the over-and misuse of anti-malarials, ...
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(Royal Society of Chemistry, 2009-08)The increasing incidence of human immunodeficiency virus (HIV) infection and the associated acquired immune deficiency syndrome (AIDS) mortality rates as well as the sometimes severe side effects of highly active anti ...
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(Institute of molecular biology and genetics, National Academy of Sciences of Ukraine, 2010)AIM: To screen mobile genetic elements (MGE) in the bacterium which caused decay of field-grown onion bulb and to study an integron and gene cassettes associated. METHODS: Polymerase chain reaction (PCR) and PCR products ...
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(Springer, 2010-02)Inhibition of polyamine biosynthesis and/or the perturbation of polyamine functionality have been exploited with success against parasitic diseases such as Trypanosoma infections. However, when the classical polyamine ...
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(Springer, 2010-02)Highly active antiretroviral therapy (HAART) has resulted in decreased mortality and morbidity from the acquired immune deficiency syndrome caused by the human immunodeficiency virus (HIV). Drug resistance and toxicity ...
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(American Chemical Society, 2010-03)Two-dimensional gel electrophoresis (2-DE) is one of the most commonly used technologies to obtain a snapshot of the proteome at any specific time. However, its application to study the Plasmodial (malaria parasite) proteome ...
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(Rural Outreach Programme, 2010-04)Mucuna bean (Mucuna pruriens L.) is grown in many parts of Kenya as a green manure/cover crop. The bean contains a high content of crude protein. However, it remains a minor food crop due to the presence of anti-nutritional ...
Now showing items 1-20 of 666