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Browsing Research Articles (Anatomy) by UP Author "Basson, Charlise"
Now showing items 1-6 of 6
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Basson, Charlise; Serem, June Cheptoo; Bipath, Priyesh; Hlophe, Y. (Wiley, 2023-07)BACKGROUND : Cutaneous melanoma is a relentless form of cancer which continues to rise in incidence. Currently, cutaneous melanoma is the leading cause of skin cancer-related mortality, which can mainly be attributed to ...
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Basson, Charlise; Phiri, Avulundiah Edwin; Gandhi, Manjunath; Anguelov, Roumen; Serem, June Cheptoo; Bipath, Priyesh; Hlophe, Yvette Nkondo (Wiley, 2024-06)CTCE-9908, a CXC chemokine receptor 4 (CXCR4) antagonist, prevents CXCR4 phosphorylation and inhibits the interaction with chemokine ligand 12 (CXCL12) and downstream signalling pathways associated with metastasis. This ...
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Basson, Charlise; Serem, June Cheptoo; Hlophe, Yvette Nkondo; Bipath, Priyesh (Wiley, 2023-10)The metastatic behavior of melanoma has accentuated the need for specific therapy targets. Compounds, namely L‐kynurenine (L‐kyn), quinolinic acid (Quin), and kynurenic acid (KA) previously displayed antiproliferative ...
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Van Strijp, Leigh-Ann; Van Rooy, Mia-Jeanne; Serem, June Cheptoo; Basson, Charlise; Oberholzer, H.M. (Taylor and Francis, 2023)Heavy metals are natural elements characterized by their relatively large atomic mass as well as high density. It can be introduced into the ecosystem by the mining of heavy metals from deep within the earth’s crust, thereby ...
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Nkandeu, D.S. (Danielle Sandra); Basson, Charlise; Joubert, Anna Margaretha; Serem, June Cheptoo; Bipath, Priyesh; Nyakudya, Trevor Tapiwa; Hlophe, Yvette Nkondo (Wiley, 2022-08)Cancer is the second leading cause of mortality worldwide. Skin cancer is the most common cancer in South Africa with nearly 20,000 reported cases every year and 700 deaths. If diagnosed early, the 5‐year survival rate ...
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Basson, Charlise; Serem, June Cheptoo; Hlophe, Yvette Nkondo; Bipath, Priyesh (Wiley, 2023-09)INTRODUCTION : The activation of the kynurenine pathway in cancer progression and metastasis through immunomodulatory pathways has drawn attention to the potential for kynurenine pathway inhibition. The activation of the ...
Now showing items 1-6 of 6