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Browsing Oral Pathology and Oral Biology by Subject "Adipose tissue"
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Ambele, Melvin Anyasi; Dhanraj, Priyanka; Giles, Rachel; Pepper, Michael Sean
(MDPI Publishing, 2020-06-16)
The formation of adipocytes during embryogenesis has been largely understudied.
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem cells which
migrate from the mesoderm to their anatomical ...
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Oloyo, Ahmed Kolade; Ambele, Melvin Anyasi; Pepper, Michael Sean
(Springer, 2017-11)
The effect of mesenchymal stromal/stem cells (MSCs) on tumour growth remains controversial. Experimental evidence supports both an inhibitory and a stimulatory effect. We have assessed factors responsible for the contrasting ...
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Dhanraj, Priyanka; Van Heerden, Marlene B.; Pepper, Michael Sean; Ambele, Melvin Anyasi
(MDPI, 2021-07)
Despite obesity being a major health concern, information on the early clinical changes that
occur in plasma and tissues during obesity development and the influence of sexual dimorphism
is lacking. This study investigated ...
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Pitere, Reabetswe R.; Van Heerden, Marlene B.; Pepper, Michael Sean; Ambele, Melvin Anyasi
(MDPI, 2022-02)
Adipogenesis, through adipocyte hyperplasia and/or hypertrophy, leads to increased
adiposity, giving rise to obesity. A genome-wide transcriptome analysis of in vitro adipogenesis in
human adipose-derived stromal/stem ...