A possible genetic predisposition to suspected hypoxic-ischaemic encephalopathy

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Authors

Holborn, Megan A.
Mellet, Juanita
Joubert, Fourie
Ballot, D.
Pepper, Michael Sean

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

Within the last decade, several studies have explored whether there might be a genetic component in hypoxic-ischaemic encephalopathy (HIE) that influences susceptibility to or outcomes following hypoxic-ischaemic injury. This review provides a comprehensive overview of the findings to date from published studies investigating the genetics of HIE. It also highlights some of the challenges faced by researchers, as well as recommendations for future research.

Description

DATA AVAILABILITY : No data was used for the research described in the article.

Keywords

Hypoxic-ischaemic encephalopathy (HIE), Genetics research, Genomics, Variants, SDG-03: Good health and well-being, SDG-15: Life on land

Sustainable Development Goals

SDG-03:Good heatlh and well-being
SDG-15:Life on land

Citation

Holborn, M.A., Mellet, J., Joubert, F. et al. 2025, 'A possible genetic predisposition to suspected hypoxic-ischaemic encephalopathy', Biochimica et Biophysica Acta - Molecular Basis of Disease, vol. 1871, no. 4, art. 167732, pp. 1-13, doi : 10.1016/j.bbadis.2025.167732.