Genotypic and phenotypic diversity of Mycobacterium tuberculosis strains in patients with concomitant pulmonary and extra-pulmonary tuberculosis

dc.contributor.advisorPeters, Remco P.H.
dc.contributor.coadvisorMbelle, Nontombi Marylucy
dc.contributor.emailsibandzedoctor@gmail.com
dc.contributor.postgraduateSibandze, Busizwe Busizwe
dc.date.accessioned2019-12-13T08:07:32Z
dc.date.available2019-12-13T08:07:32Z
dc.date.created2019/09/06
dc.date.issued2019
dc.descriptionDissertation (MSc)--University of Pretoria, 2019.
dc.description.abstractfuture, more robust or higher-resolution genomic typing tools, such as target Next Generation Sequencing (t-NGS) or metagenomic analysis are recommended to improve our understanding of the complexity of infections and for detection of both minority and major variants within extrapulmonary and pulmonary specimens for better estimation of the extent of M. tuberculosis genotypic and phenotypic heterogeneity.
dc.description.availabilityUnrestricted
dc.description.degreeMSc
dc.description.departmentMedical Microbiology
dc.identifier.citationSibandze, BB 2019, Genotypic and phenotypic diversity of Mycobacterium tuberculosis strains in patients with concomitant pulmonary and extra-pulmonary tuberculosis, MSc Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/72686>
dc.identifier.otherS2019
dc.identifier.urihttp://hdl.handle.net/2263/72686
dc.language.isoen
dc.publisherUniversity of Pretoria
dc.rights© 2019 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria.
dc.subjectUCTD
dc.subjectTuberculosis
dc.subjectPublic Health
dc.subjectMetagenomic analysis
dc.subjectGenomic typing tools
dc.subjectMolecular diagnostics
dc.subjectHealth Risks
dc.subjectPulmonary specimens
dc.subjectGenotypic heterogeneity
dc.subjectPhenotypic heterogeneity
dc.subject.otherHealth sciences theses SDG-03
dc.subject.otherSDG-03: Good health and well-being
dc.subject.otherHealth sciences theses SDG-10
dc.subject.otherSDG-10: Reduced inequalities
dc.subject.otherHealth sciences theses SDG-17
dc.subject.otherSDG-17: Partnerships for the goals
dc.titleGenotypic and phenotypic diversity of Mycobacterium tuberculosis strains in patients with concomitant pulmonary and extra-pulmonary tuberculosis
dc.typeDissertation

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