Browsing Theses and Dissertations (Pharmacology) by Subject "Alzheimer’s disease"

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Assessing the acetylcholinesterase inhibitory potential of novel pharmacophores for potential treatment of Alzheimer’s disease

Maboko, Lerato Mamabote (University of Pretoria, 2023-08)

Alzheimer’s disease (AD) is the predominant form of dementia which primarily affects the elderly. To date the aetiology of AD has not been fully elucidated, though may include: loss of cholinergic transmission; excessive ...
In vitro effect of selected medicinal plants on β-amyloid induced toxicity in neuroblastoma cells

Adewusi, Emmanuel Adekanmi (University of Pretoria, 2012-10-01)

Neurodegenerative diseases occur as a result of the breakdown and deterioration of the neurons of the central nervous system (CNS). They are commonly found in elderly people and are a major cause of morbidity and mortality, ...

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