Browsing Obstetrics and Gynaecology by Author "Willmer, Tarryn"

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Changes in subcutaneous adipose tissue microRNA expression in response to exercise training in African women with obesity

Pheiffer, Carmen; Dias, Stephanie; Mendham, Amy E.; Jack, Babalwa; Willmer, Tarryn; Eshibona, Nasr; Bendou, Hocine; Pretorius, Ashley; Goedecke, Julia H. (Nature Research, 2022-11-01)

The mechanisms that underlie exercise-induced adaptations in adipose tissue have not been elucidated, yet, accumulating studies suggest an important role for microRNAs (miRNAs). This study aimed to investigate miRNA ...
A high fat, high sugar diet induces hepatic peroxisome proliferator-activated receptor gamma coactivator 1-alpha promoter hypermethylation in male Wistar rats

Abrahams, Yoonus; Willmer, Tarryn; Patel, Oelfah; Samodien, Ebrahim; Muller, Christo J.F.; Windvogel, Shantal; Johnson, Rabia; Pheiffer, Carmen (Elsevier, 2023-11)

Previously we reported that a high fat, high sugar (HFHS) diet induced adiposity, hyperinsulinaemia, hyperleptinaemia, hypertriglyceridaemia and increased liver mass in male Wistar rats. In the present study, the mechanisms ...
A pilot investigation of genetic and epigenetic variation of FKBP5 and response to exercise intervention in African women with obesity

Willmer, Tarryn; Oosthuizen, Amberly; Dias, Stephanie; Mendham, Amy E.; Goedecke, Julia H.; Pheiffer, Carmen (Nature Research, 2022)

We investigated gluteal (GSAT) and abdominal subcutaneous adipose tissue (ASAT) DNA methylation of FKBP5 in response to a 12-week intervention in African women with obesity, as well as the efect of the rs1360780 single ...

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Browsing Obstetrics and Gynaecology by Author "Willmer, Tarryn"

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