Malaza, Nompumelelo; Pheiffer, Carmen; Dias, S.; Adam, Sumaiya(Health and Medical Publishing Group, 2023-06)
BACKGROUND : Diabetes and obesity in pregnancy have been associated with increased rates of adverse maternal and neonatal outcomes compared
with women with normoglycaemia and normal weight.
OBJECTIVE : To investigate the ...
Access to emergency obstetric care, including assisted vaginal birth and caesarean birth, is crucial for improving maternal and childbirth outcomes. However, although the proportion of births by caesarean section has ...
Hlongwane, T.M.A.G. (Tsakane); Pattinson, Robert Clive; Bergh, Anne-Marie(BMC, 2023-05-27)
INTRODUCTION : Detecting the risk of stillbirth during pregnancy remains a challenge. Continuous-wave Doppler
ultrasound (CWDU) can be used to screen for placental insufficiency, which is a major cause of stillbirths in ...
Previously we reported that a high fat, high sugar (HFHS) diet induced adiposity, hyperinsulinaemia, hyperleptinaemia,
hypertriglyceridaemia and increased liver mass in male Wistar rats. In the present study, the
mechanisms ...
Botha, Matthys Hendrik; Van der Merwe, Frederick H.; Snyman, Leon Cornelius; Dreyer, Gerrit J.; Visser, Cathy; Dreyer, Greta(Lippincott, Williams & Wilkins, 2023-07)
OBJECTIVE : Screening with primary human papillomavirus (HPV) testing has been evaluated in highly prescreened populations with lower HPV and HIV prevalence than what is the case in South Africa. High prevalence of HPV and ...
Nel, Sanja; Pattinson, Robert Clive; Vannevel, Valerie; Feucht, Ute; Mulol, Helen; Wenhold, F.A.M. (Friedeburg Anna Maria)(Cambridge University Press, 2023-08)
OBJECTIVES : Prenatal growth affects short- and long-term morbidity, mortality and growth, yet communication between prenatal and postnatal healthcare teams is often minimal. This paper aims to develop an integrated, ...
The objective of this study was to establish scientific causality and to devise criteria to implicate intrapartum hypoxia in cerebral palsy (CP)
in low-resource settings, where there is potential for an increase in damaging ...
Snyman, Leon Cornelius; Richter, Karin Louise; widowi; Dreyer, Gerrit; Botha, Matthys Hendrik; Van der Merwe, F. Haynes; Visser, Cathy; Dreyer, Greta(BMJ Publishing, 2023-05)
OBJECTIVES : Cervical cancer is preventable and caused by persistent infection with oncogenic human papilloma virus (HPV) types. HPV screening is more sensitive and is the preferred screening test. HPV screening data are ...
Preclinical studies show that the anticancer actions of vitamin D metabolites are mediated by apoptosis, inhibition of cell proliferation and induction of cell cycle arrest. Cervical cancer cells express an autocrine vitamin ...
Rimmer, Michael P.; Howie, Ruth A.; Anderson, Richard A.; Barratt, Christopher L.R.; Barnhart, Kurt T.; Beebeejaun, Yusuf; Bertolla, Ricardo Pimenta; Bhattacharya, Siladitya; Bjorndahl, Lars; Bortoletto, Pietro; Brannigan, Robert E.; Cantineau, Astrid E.P.; Caroppo, Ettore; Collura, Barbara L.; Coward, Kevin; Eisenberg, Michael L.; De Geyter, Christian; Goulis, Dimitrios G.; Henkel, Ralf R.; Ho, Vu N.A.; Hussein, Alayman F.; Huyser, Carin; Kadijk, Jozef H.; Kamath, Mohan S.; Khashaba, Shadi; Kobori, Yoshitomo; Kopeika, Julia; Kucuk, Tansu; Lujan, Saturnino; Matsaseng, Thabo Christopher; Mathur, Raj S.; McEleny, Kevin; Mitchell, Rod T.; Mol, Ben W.; Murage, Alfred M.; Ng, Ernest H.Y.; Pacey, Allan; Perheentupa, Antti H.; Du Plessis, Stefan; Rives, Nathalie; Sarris, Ippokratis; Schlegel, Peter N.; Shabbir, Majid; Smiechowski, Maciej; Subramanian, Venkatesh; Sunkara, Sesh K.; Tarlarzis, Basil C.; Tuttelmann, Frank; Tuttelmann, Frank; Vail, Andy; Van Wely, Madelon; Vazquez-Levin, Monica H.; Vuong, Lan N.; Alex Y. Wang; Wang, Rui; Zini, Armand; Farquhar, Cindy M.; Niederberger, Craig; Duffy, James M.N.(Oxford University Press, 2022-03)
STUDY QUESTION : We aim to develop, disseminate and implement a minimum data set, known as a core outcome set, for future
male infertility research.
WHAT IS KNOWN ALREADY : Research into male infertility can be challenging ...
Nachega, Jean B.; Sam-Agudu, Nadia A.; Machekano, Rhoderick N.; Rosenthal, Philip J.; Schell, Sonja; De Waard, Liesl; Bekker, Adrie; Gachuno, Onesmus W.; Kinuthia, John; Mwongeli, Nancy; Budhram, Samantha; Vannevel, Valerie; Soma-Pillay, Priya; Prozesky, Hans W.; Taljaard, Jantjie; Parker, Arifa; Agyare, Elizabeth; Opoku, Akwasi Baafuor; Makarfi, Aminatu Umar; Abdullahi, Asara M.; Adirieje, Chibueze; Ishoso, Daniel Katuashi; Pipo, Michel Tshiasuma; Tshilanda, Marc B.; Nswe, Christian Bongo-Pasi; Ditekemena, John; Sigwadhi, Lovemore Nyasha; Nyasulu, Peter S.; Hermans, Michel P.; Sekikubo, Musa; Musoke, Philippa; Nsereko, Christopher; Agbeno, Evans K.; Yeboah, Michael Yaw; Umar, Lawal W.; Ntakwinja, Mukanire; Mukwege, Denis M.; Birindwa, Etienne Kajibwami; Mushamuka, Serge Zigabe; Smith, Emily R.; Mills, Edward J.; Otshudiema, John Otokoye; Mbala-Kingebeni, Placide; Tamfum, Jean-Jacques Muyembe; Zumla, Alimuddin; Tsegaye, Aster; Mteta, Alfred; Sewankambo, Nelson K.; Suleman, Fatima; Adejumo, Prisca; Anderson, Jean R.; Noormahomed, Emilia V.; Deckelbaum, Richard J.; Stringer, Jeffrey S.A.; Mukalay, Abdon; Taha, Taha E.; Fowler, Mary Glenn; Wasserheit, Judith N.; Masekela, Refiloe; Mellors, John W.; Siedner, Mark J.; Myer, Landon; Kengne, Andre-Pascal; Yotebieng, Marcel; Mofenson, Lynne M.; Langenegger, Eduard; AFREhealth Research Collaboration on COVID-19 and Pregnancy(Oxford University Press, 2022-06-08)
BACKGROUND : Few data are available on COVID-19 outcomes among pregnant women in sub-Saharan Africa (SSA), where high-risk comorbidities are prevalent. We investigated the impact of pregnancy on SARS-CoV-2 infection and ...
The presence of squamous cell carcinoma (SCC) on endometrial histology raises the possibility of a primary endometrial carcinoma, as well as secondary endometrial involvement by SCC from another site, especially the cervix. ...
The 3T3-L1 murine adipocyte cell line remains one of the most widely used models to study the
mechanisms of obesity and related pathologies. Most studies investigate such mechanisms using mature
adipocytes that have been ...
It can be argued that there are three colliding pandemics that are currently affecting the planet and its people: COVID-19, global inequities and climate change. Regrettably, these are all the result of human action or ...
The importance of iron for overall health in humans cannot be overstated and its extremely widespread biological functions include electron transfer, intercellular signalling, catalysis, and oxygen binding and transport. ...
Snyman, Leon Cornelius(Netherlands Press, 2022-07)
The doctor-patient relationship, although extremely important and essential to ensure optimal treatment outcomes, remains complicated. This relationship allows two people, unfamiliar with each other, with different value ...
Mbambu, T.; Snyman, Leon Cornelius(Netherlands Press, 2022-01)
Transverse vaginal septum is a rare congenital anomaly. It is one of the variants of müllerian duct anomalies which
results from defective fusion or recanalization of the vaginal and müllerian organs. It can present with ...
Placental malaria occurs when there is sequestration of Plasmodium falciparum infected red blood cells in the placenta. This is the primary mechanism by which malaria in pregnancy perpetuates its adverse perinatal outcomes ...
Chigumadzi, Peter Farai; Lubega, Sheila Nansamba; Bryant, Emma P.; Snyman, Leon Cornelius(Netherlands Press, 2022-11)
BACKGROUND : The South African Choice on Termination of Pregnancy Act was passed in 1996, legalizing a women’s right to request a termination of pregnancy. Despite this legislation, there are still a large number of women ...
Nakanyane, T.E.; Molokoane, Felicia; Snyman, Leon Cornelius(The Netherlands Press, 2022-01)
BACKGROUND : Acute kidney injury (AKI) in pregnancy presents with complexities relating to the pathophysiology
of the disease. It is associated with an increased risk of maternal and perinatal morbidity and mortality. ...