Browsing Research Articles (Urology) by UP Author "De Jager, Christiaan"

Browsing Research Articles (Urology) by UP Author "De Jager, Christiaan"

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  • Alterations in male reproductive hormones in relation to environmental DDT exposure 
    Bornman, Maria S. (Riana); Delport, Rhena; Farías, Paulina; Aneck-Hahn, Natalie Hildegard; Patrick, Sean Mark; Millar, Robert P.; De Jager, Christiaan (Elsevier, 2018-04)
    DDT [1, 1, 1-trichloro-2,2-bis (p-chlorophenyl)-ethane] compounds are used for indoor residual spraying (IRS) to control malaria mosquitoes. DDT is an endocrine disruptor chemical in experimental conditions, but little is ...
  • Changes in retinol-binding protein concentrations and thyroid homeostasis with non-occupational exposure to DDT 
    Delport, Rhena; Bornman, Maria S. (Riana); MacIntyre, Una Elizabeth; Oosthuizen, Nicholette M.; Becker, Piet J.; Aneck-Hahn, Natalie Hildegard; De Jager, Christiaan (National Institute of Environmental Health Sciences (NIEHS), 2010-12)
    BACKGROUND: The insecticide dichlorodiphenyltrichloroethane (DDT) has been used for malaria vector control in the northern and eastern parts of the Vhembe District of Limpopo Province, South Africa, since 1945. Bioaccumulation ...
  • DDT and urogenital malformations in newborn boys in a malarial area 
    Bornman, Maria S. (Riana); De Jager, Christiaan; Worku, Zeleke; Farias, Paulina; Reif, Simon (Wiley-Blackwell, 2010-08)
    OBJECTIVE: To determine the risk of external urogenital birth defects (UGBDs) in newborn boys from a malarial area currently sprayed with technical DDT, 1,1,1-trichloro-2,2- bis(4-chlorophenyl) ethane (DDT), as increased ...
  • DDT exposure levels and semen quality of young men from a malaria area in South Africa 
    De Jager, Christiaan; Aneck-Hahn, Natalie Hildegard; Bornman, Maria S. (Riana); Farias, Paulina; Spano, Marcello (BioMed Central, 2012-10-15)
    No abstract available.
  • Endocrine disrupting chemicals in commercially available cling film brands in South Africa 
    De Jager, Christiaan; Aneck-Hahn, Natalie Hildegard; Van Zijl, Magdalena Catherina; Hayward, Stefan; Swart, Pieter; Genthe, Bettina (Taylor and Francis, 2019)
    Cling films comprise of plasticizers which are known endocrine disrupting chemicals (EDCs). Cling films are commonly used for food packaging and EDCs may leach into food, increasing exposure, leading to adverse health ...
  • Endocrine disruptors and health effects in Africa : a call for action 
    Bornman, Maria S. (Riana); Aneck-Hahn, Natalie Hildegard; De Jager, Christiaan; Wagenaar, Gesina M.; Bouwman, Hindrik; Barnhoorn, Irene E.J.; Patrick, Sean Mark; Vandenberg, Laura N.; Kortenkamp, Andreas; Blumberg, Bruce; Kimmins, Sarah; Jegou, Bernard; Auger, Jacques; DiGangi, Joseph; Heindel, Jerrold J. (National Institute of Environmental Health Sciences, 2017)
    BACKGROUND : Africa faces a number of unique environmental challenges. Unfortunately, it lacks the infrastructure needed to support the comprehensive environmental studies that could provide the scientific basis to inform ...
  • Estrogenic activity, chemical levels and health risk assessment of municipal distribution point water from Pretoria and Cape Town, South Africa 
    Van Zijl, Magdalena Catherina; Aneck-Hahn, Natalie Hildegard; Swart, Pieter; Hayward, Stefan; Genthe, Bettina; De Jager, Christiaan (Elsevier, 2017-11)
    Endocrine disrupting chemicals (EDCs) are ubiquitous in the environment and have been detected in drinking water from various countries. Although various water treatment processes can remove EDCs, chemicals can also migrate ...
  • Estrogenic activity, selected plasticizers and potential health risks associated with bottled water in South Africa 
    Aneck-Hahn, Natalie Hildegard; Van Zijl, Magdalena Catherina; Swart, Pieter; Truebody, Barry; Genthe, Bettina; Charmier, Jessica; De Jager, Christiaan (IWA Publishing, 2018-04)
    Potential endocrine disrupting chemicals (EDCs) are present in bottled water from various countries. In South Africa (SA), increased bottled water consumption and concomitant increases in plastic packaging create important ...
  • Immunohistochemical study of nuclear changes associated with male germ cell death and spermiogenesis 
    McClusky, Leon M.; Patrick, Sean Mark; Barnhoorn, Irene E.J.; Van Dyk, Jacobus C.; De Jager, Christiaan; Bornman, Maria S. (Riana) (Springer, 2009-08)
    In a previous study on the effects of gestational and lactational exposure of para-nonylphenol on male rats, we noted in both induced and uninduced rats, that variations in cleaved caspase- 3 immunostaining patterns were ...
  • Oestrogenic activity in drinking waters from a rural area in the Waterberg District, Limpopo Province, South Africa 
    Aneck-Hahn, Natalie Hildegard; Bornman, Maria S. (Riana); De Jager, Christiaan (Water Research Council, 2009-04)
    In South Africa, limited data are available regarding possible oestrogenic activity in the aquatic systems and especially drinking water. Water in the rural areas is often contaminated with a complex mixture of toxic ...
  • Oestrogenicity and chemical target analysis of water from small-sized industries in Pretoria, South Africa 
    Mahomed, Shenaaz Ismail; Voyi, K.V.V. (Kuku); Aneck-Hahn, Natalie Hildegard; De Jager, Christiaan (Water Research Council, 2008)
    Increasing concern about endocrine disrupting chemicals (EDCs) and their effects on humans, animals and the environment resulted in this study being conducted. Water from 7 sites in the Pretoria West area (South Africa), ...
  • Pesticide residues and estrogenic activity in fruit and vegetables sampled from major fresh produce markets in South Africa 
    Mutengwe, Mbulaheni Thomas; Aneck-Hahn, Natalie Hildegard; Korsten, Lise; Van Zijl, Magdalena Catherina; De Jager, Christiaan (Taylor and Francis, 2016)
    Food is likely to be one of the major pathways through which people are exposed to endocrinedisrupting chemicals. With the exception of residual effects, there are concerns that a number of naturally occurring and synthetic ...
  • The Pine river statement : human health consequences of DDT use 
    Eskenazi, Brenda; Chevrier, Jonathan; Rosas, Lisa Goldman; Anderson, Henry A.; Bornman, Maria S. (Riana); Bouwman, Henk; Chen, Aimin; Cohn, Barbara A.; De Jager, Christiaan; Henshel, Diane S.; Leipzig, Felicia; Leipzig, John S.; Lorenz, Edward C.; Snedeker, Suzanne M.; Stapleton, Darwin (National Institute of Environmental Health Sciences (NIEHS), 2009-09)
    OBJECTIVES: Dichlorodiphenyltrichloroethane (DDT) was used worldwide until the 1970s, when concerns about its toxic effects, its environmental persistence, and its concentration in the food supply led to use restrictions ...
  • Simultaneous exposure to low concentrations of dichlorodiphenyltrichloroethane, deltamethrin, nonylphenol and phytoestrogens has negative effects on the reproductive parameters in male Spraque-Dawley rats 
    Kilian, Elmare; Delport, Rhena; Bornman, Maria S. (Riana); De Jager, Christiaan (Blackwell, 2007-08)
    Many reports suggest that male reproductive health has deteriorated over the last decades, possibly due to environmental contaminants that act as endocrine disruptors. This hypothesis was tested in Sprague-Dawley rats ...
  • Sperm chromatin integrity in DDT-exposed young men living in a malaria area in the Limpopo Province, South Africa 
    De Jager, Christiaan; Aneck-Hahn, Natalie Hildegard; Bornman, Maria S. (Riana); Farias, Paulina; Leter, G.; Eleuteri, P.; Rescia, M.; Spanò, M. (Oxford University Press, 2009-07)
    There is mounting evidence that deteriorated semen quality may be associated with increased serum concentration of 1,1,1-trichloro-2,2-bis(chlorodiphenyl)ethane (DDT) and its metabolites. The problem is exacerbated in ...
  • Stage-related increase in the proportion of apoptotic germ cells and altered frequencies of stages in the spermatogenic cycle following gestational, lactational, and direct exposure of male rats to p-nonylphenol 
    McClusky, Leon M.; De Jager, Christiaan; Bornman, Maria S. (Riana) (Oxford University Press, 2007-01)
    The cumulative effects of environmental toxicants, for example, the alkylphenol, para-nonylphenol (p-NP) are of concern. Our previous study showed that p-NP reduced several testicular morphometric parameters, including ...
  • Standards in semen examination : publishing reproducible and reliable data based on high-quality methodology 
    Bjorndahl, Lars; Barratt, Christopher L.R.; Mortimer, David; Agarwal, Ashok; Aitken, Robert J.; Alvarez, Juan G.; Aneck-Hahn, Natalie Hildegard; Arver, Stefan; Baldi, Elisabetta; Bassas, Lluis; Boitrelle, Florence; Bornman, Maria S. (Riana); Carrell, Douglas T.; Castilla, Jose A.; Cerezo Parra; Parra, Gerardo Cerezo; Check, Jerome H.; Cuasnicu, Patricia S.; Darney, Sally Perreault; De Jager, Christiaan; De Jonge, Christopher J.; Drevet, Joel R.; Drobnis, Erma Z.; Du Plessis, Stefan S.; Eisenberg, Michael L.; Esteves, Sandro C.; Evgeni, Evangelini A.; Ferlin, Alberto; Garrido, Nicolas; Giwercman, Aleksander; Goovaerts, Ilse G.F.; Haugen, Trine B.; Henkel, Ralf; Henningsohn, Lars; Hofmann, Marie-Claude; Hotaling, James M.; Jedrzejczak, Piotr; Jouannet, Pierre; Jorgensen, Niels; Kirkman Brown, Jackson C.; Krausz, Csilla; Kurpisz, Maciej; Kvist, Ulrik; Lamb, Dolores J.; Levine, Hagai; Loveland, Kate L.; McLachlan, Robert, I.; Mahran, Ali; Maree, Liana; Da Silva, Sarah Martins; Mbizvo, Michael T.; Meinhardt, Andreas; Menkveld, Roelof; Mortimer, Sharon T.; Moskovtsev, Sergey; Muller, Charles H.; Jose Munuce, Maria; Muratori, Monica; Niederberger, Craig; O'Flaherty, Cristian; Oliva, Rafael; Ombelet, Willem; Pacey, Allan A.; Palladino, Michael A.; Ramasamy, Ranjith; Ramos, Liliana; Rives, Nathalie; Roldan, Eduardo Rs; Rothmann, Susan; Sakkas, Denny; Salonia, Andrea; Sanchez-Pozo, Maria Cristina; Sapiro, Rosanna; Schlatt, Stefan; Schlegel, Peter N.; Schuppe, Hans-Christian; Shah, Rupin; Skakkebaek, Niels E.; Teerds, Katja; Toskin, Igor; Tournaye, Herman; Turek, Paul J.; Van der Horst, Gerhard; Vazquez-Levin, Monica; Wang, Christina; Wetzels, Alex; Zeginiadou, Theodosia; Zini, Armand (Oxford University Press, 2022-10)
    Biomedical science is rapidly developing in terms of more transparency, openness and reproducibility of scientific publications. This is even more important for all studies that are based on results from basic semen ...
  • Testicular microlithiasis and neoplastic lesions in wild eland (Tragelaphus oryx) : possible effects of exposure to environmental pollutants? 
    Bornman, Maria S. (Riana); Barnhoorn, Irene E.J.; De Jager, Christiaan; Veeramachaneni, D.N.R. (Elsevier, 2010-05)
    The purpose of the study was to compare wildlife in the proximity and away from the sources of known industrial pollution. Macroscopic, focal, gritty areas that appeared white were observed in the testes of all 24 South ...
  • Veterinary growth promoters in cattle feedlot runoff : estrogenic activity and potential effects on the rat male reproductive system 
    Patrick, Sean Mark; Aneck-Hahn, Natalie Hildegard; Van Wyk, Susan; Van Zijl, Magdelena Catherina; Huma, Mampedi; De Jager, Christiaan (Springer, 2020-04)
    The contribution of veterinary growth promoters (VGP) to the environmental burden of endocrine-disrupting chemicals (EDCs) is largely unknown. At cattle feedlots, the excrement of cattle may contain VGPs, which can contaminate ...