• Renal papillary necrosis (RPN) in an African population : disease patterns, relevant pathways, and management 

  Gaudji, Guy Roger; Bida, M.; Conradie, Marius; Damane, Botle Precious; Bester, Megan (MDPI, 2023-01)

  Renal papillary necrosis (RPN) is characterized by coagulative necrosis of the renal medullary pyramids and papillae. Multiple conditions and toxins are associated with RPN. Several RPN risk factors, or POSTCARDS, have ...
• Standards in semen examination : publishing reproducible and reliable data based on high-quality methodology 

  Bjorndahl, Lars; Barratt, Christopher L.R.; Mortimer, David; Agarwal, Ashok; Aitken, Robert J.; Alvarez, Juan G.; Aneck-Hahn, Natalie Hildegard; Arver, Stefan; Baldi, Elisabetta; Bassas, Lluis; Boitrelle, Florence; Bornman, Maria S. (Riana); Carrell, Douglas T.; Castilla, Jose A.; Cerezo Parra; Parra, Gerardo Cerezo; Check, Jerome H.; Cuasnicu, Patricia S.; Darney, Sally Perreault; De Jager, Christiaan; De Jonge, Christopher J.; Drevet, Joel R.; Drobnis, Erma Z.; Du Plessis, Stefan S.; Eisenberg, Michael L.; Esteves, Sandro C.; Evgeni, Evangelini A.; Ferlin, Alberto; Garrido, Nicolas; Giwercman, Aleksander; Goovaerts, Ilse G.F.; Haugen, Trine B.; Henkel, Ralf; Henningsohn, Lars; Hofmann, Marie-Claude; Hotaling, James M.; Jedrzejczak, Piotr; Jouannet, Pierre; Jorgensen, Niels; Kirkman Brown, Jackson C.; Krausz, Csilla; Kurpisz, Maciej; Kvist, Ulrik; Lamb, Dolores J.; Levine, Hagai; Loveland, Kate L.; McLachlan, Robert, I.; Mahran, Ali; Maree, Liana; Da Silva, Sarah Martins; Mbizvo, Michael T.; Meinhardt, Andreas; Menkveld, Roelof; Mortimer, Sharon T.; Moskovtsev, Sergey; Muller, Charles H.; Jose Munuce, Maria; Muratori, Monica; Niederberger, Craig; O'Flaherty, Cristian; Oliva, Rafael; Ombelet, Willem; Pacey, Allan A.; Palladino, Michael A.; Ramasamy, Ranjith; Ramos, Liliana; Rives, Nathalie; Roldan, Eduardo Rs; Rothmann, Susan; Sakkas, Denny; Salonia, Andrea; Sanchez-Pozo, Maria Cristina; Sapiro, Rosanna; Schlatt, Stefan; Schlegel, Peter N.; Schuppe, Hans-Christian; Shah, Rupin; Skakkebaek, Niels E.; Teerds, Katja; Toskin, Igor; Tournaye, Herman; Turek, Paul J.; Van der Horst, Gerhard; Vazquez-Levin, Monica; Wang, Christina; Wetzels, Alex; Zeginiadou, Theodosia; Zini, Armand (Oxford University Press, 2022-10)

  Biomedical science is rapidly developing in terms of more transparency, openness and reproducibility of scientific publications. This is even more important for all studies that are based on results from basic semen ...
• AI and precision oncology in clinical cancer genomics : from prevention to targeted cancer therapies-an outcomes based patient care 

  Dlamini, Zodwa; Skepu, Amanda; Kim, Namkug; Mkhabele, Mahlori; Khanyile, Richard; Molefi, Thulo; Mbatha, Sikhumbuzo; Setlai, Botle; Mulaudzi, Thanyani Victor; Mabongo, Mzubanzi; Bida, Nndweleni Meshack; Kgoebane-Maseko, Minah; Mathabe, Kgomotso; Lockhat, Zarina I.; Kgokolo, C.M.; Chauke-Malinga, Nkhensani; Ramagaga, Serwalo; Hull, Rodney (Elsevier, 2022)

  Precision medicine is the personalization of medicine to suit a specific group of people or even an individual patient, based on genetic or molecular profiling. This can be done using genomic, transcriptomic, epigenomic ...
• Influence of the microbiome metagenomics and epigenomics on gastric cancer 

  Mathebela, Precious; Damane, Botle Precious; Mulaudzi, Thanyani Victor; Mkhize-Khwitshana, Zilungile Lynette; Gaudji, Guy Roger; Dlamini, Zodwa (MDPI, 2022-11)

  Gastric cancer (GC) is one of the major causes of cancer deaths worldwide. The disease is seldomly detected early and this limits treatment options. Because of its heterogeneous and complex nature, the disease remains ...
• Clinician’s guide to perineal and obstetric anal sphincter injury 

  Paterson, Frances; Retief, Francois; Swart, Paul; Abdool, Zeelha (In House Publications, 2020-07)

  Perineal trauma is a common consequence of vaginal childbirth. This may be spontaneous or an iatrogenic event following an episiotomy, or a combination of the two. One UK study states that up to 85% of women experience ...
• Many voices in a choir: tumor-induced neurogenesis and neuronal driven alternative splicing sound like suspects in tumor growth and dissemination 

  Dlamini, Zodwa; Mathabe, Kgomotso; Padayachy, Llewellyn; Marima, Rahaba; Evangelou, George; Syrigos, Konstantinos N.; Bianchi, Arianna; Lolas, Georgios; Hull, Rodney (MDPI, 2021-05)

  During development, as tissues expand and grow, they require circulatory, lymphatic, and nervous system expansion for proper function and support. Similarly, as tumors arise and develop, they also require the expansion ...
• Prostate cancer racial, socioeconomic, geographic disparities : targeting the genomic landscape and splicing events in search for diagnostic, prognostic and therapeutic targets 

  Marima, Rahaba; Hull, Rodney; Mathabe, Kgomotso; Setlai, Botle Precious; Batra, Jyotsna; Sartor, Oliver; Mehrotra, Ravi; Dlamini, Zodwa (e-Century Publishing, 2021-04)

  Prostate cancer (PCa) is one of the leading causes of deaths in men globally. This is a heterogeneous and complex disease that urgently warrants further insight into its pathology. Developed countries have thus far the ...
• Veterinary growth promoters in cattle feedlot runoff : estrogenic activity and potential effects on the rat male reproductive system 

  Patrick, Sean Mark; Aneck-Hahn, Natalie Hildegard; Van Wyk, Susan; Van Zijl, Magdelena Catherina; Huma, Mampedi; De Jager, Christiaan (Springer, 2020-04)

  The contribution of veterinary growth promoters (VGP) to the environmental burden of endocrine-disrupting chemicals (EDCs) is largely unknown. At cattle feedlots, the excrement of cattle may contain VGPs, which can contaminate ...
• Endocrine-disrupting activity of the fungicide mancozeb used in the Vhembe District of South Africa 

  Seshoka, M.F.; Van Zijl, Magdalena Catherina; Aneck-Hahn, Natalie Hildegard; Barnhoorn, I.E.J. (NISC (Pty) Ltd and Informa UK Limited (trading as Taylor & Francis Group), 2021)

  Many chemicals released into the environment are believed to disrupt normal endocrine functions in humans and animals. A major group of endocrine disrupting chemicals (EDCs) that could be responsible for reproductive defects ...
• A qualitative exploration of South African men’s perceived effects of androgen deprivation therapy (ADT) as a treatment for advanced prostate cancer 

  Gray, Peter B.; Meintjes, F.; Moshokwa, Evelyn; Mathabe, Kgomotso (Taylor and Francis, 2020)

  OBJECTIVE : We undertake qualitative research with men treated in a Pretoria, South Africa Oncology clinic to address men’s self-reported experiences on androgen deprivation therapy (ADT). METHODS : Analyses rely upon 22 ...
• Removal of pharmaceutical' estrogenic activity of sequencing batch reactor effluents assessed in the T47D-KBluc report 

  Kasonga, Teddy Kabeya; Coetzee, Martie A.A.; Van Zijl, Magdalena Catherina; Momba, Maggy Ndombo Benteke (Elsevier, 2019-06)

  Various water treatment processes may be ineffective to remove pharmaceutical compounds (PhCs) and their by-products, leading to endocrine-disruptive activity that might be detrimental to wildlife and human health. This ...
• Data on UPLC/MS method validation for the biodegradation of pharmaceuticals and intermediates by a fungal consortium and on T47DK-Bluc reporter gene assay to assess the reduction of their estrogenic activity 

  Kasonga, Teddy Kabeya; Coetzee, Martie A.A.; Van Zijl, Magdalena Catherina; Momba, Maggy Ndombo Benteke (Elsevier, 2019-08)

  In term of pharmaceutical and their intermediate compounds analysis, UPLC/MS method is a valuable equipment to achieve better confirmation on their biodegradation by fungi. The T47DKBluc reporter gene assay is an ...
• Best practice recommendations for bladder management in spinal cord-afflicted patients in South Africa 

  Theron, Francois; Wilson, V.; Scriba, E.; Campbell, R.; Van Zyl, M. (Health and Medical Publishing Group, 2019)

  Recent research on the standard of care and related quality of life of the spinal cord-afflicted community in South Africa (SA) has revealed significant gaps in practice, and challenges regarding levels of care and access ...
• Endocrine disrupting chemicals in commercially available cling film brands in South Africa 

  De Jager, Christiaan; Aneck-Hahn, Natalie Hildegard; Van Zijl, Magdalena Catherina; Hayward, Stefan; Swart, Pieter; Genthe, Bettina (Taylor and Francis, 2019)

  Cling films comprise of plasticizers which are known endocrine disrupting chemicals (EDCs). Cling films are commonly used for food packaging and EDCs may leach into food, increasing exposure, leading to adverse health ...
• Estrogenic activity, selected plasticizers and potential health risks associated with bottled water in South Africa 

  Aneck-Hahn, Natalie Hildegard; Van Zijl, Magdalena Catherina; Swart, Pieter; Truebody, Barry; Genthe, Bettina; Charmier, Jessica; De Jager, Christiaan (IWA Publishing, 2018-04)

  Potential endocrine disrupting chemicals (EDCs) are present in bottled water from various countries. In South Africa (SA), increased bottled water consumption and concomitant increases in plastic packaging create important ...
• Household fuel use and biomarkers of inflammation and respiratory illness among rural South African women 

  Misra, Ankita; Longnecker, Matthew P.; Dionisio, Kathie L.; Bornman, Maria S. (Riana); Travlos, Gregory S.; Brar, Sukhdev; Whitworth, Kristina W. (Elsevier, 2018-10)

  Though literature suggests a positive association between use of biomass fuel for cooking and inflammation, few studies among women in rural South Africa exist. We included 415 women from the South African Study of Women ...
• Male reproductive health statement (XIIIth International Symposium on Spermatology, May 9th-12th 2018, Stockholm, Sweden) 

  Levine, Hagai; Mohri, Hideo; Ekbom, Anders; Ramos, Liliana; Parker, Geoff; Roldan, Eduardo; Jovine, Luca; Koelle, Sabine; Lindstrand, Anna; Immler, Simone; Mortimer, Sharon; Mortimer, David; Van der Horst, Gerhard; Ishijima, Sumio; Aneck-Hahn, Natalie Hildegard; Baldi, Elisabetta; Menkveld, Roelof; Rothmann, Susan A.; Giwercman, Aleksander; Giwercman, Yvonne; Holmberg, Mats; Kvist, Ulrik; Bjorndahl, Lars; Holmberg, Rebecka; Arver, Stefan; Flanagan, John; Drevet, Joel R (BioMed Central, 2018-10-29)

  On the occasion of the XIIIth International Symposium on Spermatology held from 9 to 13 May 2018 in Stockholm (Sweden), participants (guest speakers and audience) collectively felt the need to make a public statement on ...
• The South African guidelines on Enuresis—2017 

  Adam, Ahmed; Claassen, Frederik; Coovadia, Ashraf; De Maayer, Tim; Fockema, Margaret; Fredericks, Joy; Gottlich, Errol; Grindell, Lizelle; Haffejee, Mohamed; Lazarus, John; Levy, Cecil; Mathabe, Kgomotso; McCulloch, Mignon; Moonsamy, Glenda; Moshokwa, Evelyn; Mutambirwa, Shingai; Patel, Haroun; Van der Merwe, Andre; Van Heerden, Izak J.; Van Vijk, Frans; Deshpande, Aniruddh; Smith, Grahame; Hoebeke, Piet (Elsevier, 2018-03)

  INTRODUCTION : Enuresis (or Nocturnal Enuresis) is defined as discreet episodes of urinary incontinence duringsleep in children over 5 years of age in the absence of congenital or acquired neurological disorders. RECOMMENDATIONS ...
• Prenatal exposure to DDT and pyrethroids for malaria control and child neurodevelopment : the VHEMBE Cohort, South Africa 

  Eskenazi, Brenda; An, Sookee; Rauch, Stephen A.; Coker, Eric S.; Maphula, Angelina; Obida, Muvhulawa; Crause, Madelein; Kogut, Katherine R.; Bornman, Maria S. (Riana); Chevrier, Jonathan (National Institute of Environmental Health Sciences, 2018-04-06)

  BACKGROUND : Although indoor residual spraying (IRS) with dichlorodiphenyltrichloroethane (DDT) and pyrethroids effectively controls malaria, it potentially increases human exposure to these insecticides. Previous studies ...
• Analysis of endocrine activity in drinking water, surface water and treated wastewater from six countries 

  Leusch, Frederic D.L.; Neale, Peta A.; Arnal, Charlotte; Aneck-Hahn, Natalie Hildegard; Balaguer, Patrick; Bruchet, Auguste; Escher, Beate I.; Esperanza, Mar; Grimaldi, Marina; Leroy, Gaela; Scheurer, Marco; Schlichting, Rita; Schriks, Merijn; Hebert, Armelle (Elsevier, 2018-08)

  The aquatic environment can contain numerous micropollutants and there are concerns about endocrine activity in environmental waters and the potential impacts on human and ecosystem health. In this study a complementary ...

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