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Bluetongue virus was found to induce interferon in mouse embryo (ME) cells and in mice. Different strains of bluetongue virus differed in their ability to induce interferon. Interferon production in ME cells commences after a 5 hour lag phase and the cells continue to produce interferon for 20 hours. Isolated double-stranded bluetongue virus RNA was found to induce maximum titres of interferon in mice approximately 4 hours earlier than was the case with whole virus.
Description:
The articles have been scanned in colour with a HP Scanjet 5590; 300dpi.
Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.