Preparation and properties of a crude extract toxic to guinea-pigs from Pachystigma pygmaeum, a plant causing heart failure in ruminants

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dc.contributor.author Potgieter, D.J.J.
dc.contributor.editor Bigalke, R.D.
dc.contributor.upauthor Verschoor, J.A. (Jan Adrianus), 1953-
dc.date.accessioned 2015-11-05T06:38:39Z
dc.date.available 2015-11-05T06:38:39Z
dc.date.created 2015
dc.date.issued 1984
dc.description The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en_ZA
dc.description.abstract Pachystigma pygmaeum is a rubiaceous plant which causes heart failure after ingestion by ruminants. Isolation or characterization of a toxic entity has hitherto been unsuccessful. Extraction of the plant material with water or organic solvents gave poor yields of toxicity in guinea-pigs because of some unusual properties of the toxic entity. We present a method whereby liberation of a toxic entity from the plant material was achieved by fermentation with baker's yeast to give a crude extract with sufficient yield of toxicity for use in further isolation work. en_ZA
dc.description.librarian am2015 en_ZA
dc.description.sponsorship Department of Agriculture. en_ZA
dc.identifier.citation Verschoor, JA & Potgieter, DJJ 1984, 'Preparation and properties of a crude extract toxic to guinea-pigs from Pachystigma pygmaeum, a plant causing heart failure in ruminants', Onderstepoort Journal of Veterinary Research, vol. 51, no. 4, pp. 245-248. en_ZA
dc.identifier.issn 0330-2465
dc.identifier.uri http://hdl.handle.net/2263/50356
dc.language.iso en en_ZA
dc.publisher Published by The Government Printer, Pretoria en_ZA
dc.rights ©ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©University of Pretoria. Dept. of Library Services (digital). en_ZA
dc.subject Veterinary medicine en_ZA
dc.subject.lcsh Veterinary medicine -- South Africa
dc.title Preparation and properties of a crude extract toxic to guinea-pigs from Pachystigma pygmaeum, a plant causing heart failure in ruminants en_ZA
dc.type Article en_ZA


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