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Bioinformatics and Computational Biology Unit
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Recent Submissions
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(Elsevier, 2024-02)Artemisia afra is an aromatic shrub used as a herbal remedy in southern Africa for various disorders, including coughs, colds, influenza, and, most notably, for the prophylaxis and treatment of Plasmodium falciparum ...
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(University of Pretoria, 2023)Cystic Fibrosis is a genetic disease caused by variants in the CFTR gene. It is one of the most thoroughly studied genetic diseases, with remarkable advances being seen in the ability to diagnose and specifically treat CF ...
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(Springer, 2023-12)Please read abstract in the article.
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(American Society for Microbiology, 2022-09-06)Listeria species (spp.) are contaminants that can survive in food, on equipment, and on food processing premises if appropriate hygiene measures are not used. Homologous stress tolerance genes, virulence gene clusters such ...
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(Springer, 2022-04)Precipitation is one of the major constraints influencing the diversity, structure, and activity of soil microbial communities in desert ecosystems. However, the effect of changes in precipitation on soil microbial communities ...
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(Springer, 2022-03)Macadamia nuts are known globally for their high quality and economic value. Global macadamia commercial nut production amounts to 60,000 metric tonnes and is increasing steadily. South Africa is the leading producer with ...
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(Elsevier, 2023-02)This study was conducted to determine the phylogenies of Salmonella strains isolated from cross-sectional studies conducted at hatcheries, broiler farms, processing plants, and retail outlets (broiler production chain) in ...
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(Nature Research, 2021-03)A metagenomic approach was used to study the gut microbiome of Haemonchus contortus feld strains and that of its predilection site, the abomasum of Dohne Merino sheep. The abomasum contents and H. contortus were collected ...
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(Genomic Standards Consortium, 2016-09-09)The members of the genus Thermoactinomyces are known for their protein degradative capacities. Thermoactinomyces sp. strain AS95 is a Gram-positive filamentous bacterium, isolated from moderately saline water in the ...
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(University of Pretoria, 2011-06-07)The importance of Cytotoxic T-Cell (CTL) reponses during the course of intracellular infections has received a lot of attention during the past few decades. CTLs respond to epitopes presented by the Major Histocompatibility ...
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(Bentham Science, 2009-03)A configuration space of homologous protein sequences (or CSHP) has been recently constructed based on pairwise comparisons, with probabilities deduced from Z-value statistics (Monte Carlo methods applied to pairwise ...
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(BioMed Central, 2008-08)BACKGROUND: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information for large scale sequence analysis and ...
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(Elsevier, 2007-02)Spermidine synthase is currently considered as a promising drug target in the malaria parasite, Plasmodium falciparum, due to the vital role of spermidine in the activation of the eukaryotic translation initiation factor ...