Stem cells: current reality & future promise

Abstract

Die snel ontwikkelende terrein van stamselnavorsing skep voortdurend hoë verwagtinge by pasiënte. Stamselle is ongedifferensieerde selle wat die vermoë besit om hulself te hernu en wat deur differensiëring in al die gespesialiseerde seltipes in die liggaam kan ontwikkel as hulle aan bepaalde omgewingsprikkels blootgestel word. Volwasse stamselle word in feitlik alle weefsel van die liggaam aangetref waarvan die bekendste sekerlik beenmurg is. Die etiese geskille rondom stamselle word egter grootliks deur embrioniese stamselle veroorsaak. Die huidige terapeutiese aanwendings van stamselle sluit beenmurgoorplantings in. In die toekoms sal stamselle waarskynlik onder meer aangewend word in die behandeling van siektes wat die hart, sentrale senustelsel en die endokrienstelsel aantas.

The rapidly evolving field of stem cell research continues to raise great hope among patients. Stem cells are undifferentiated cells capable of self-renewal that can differentiate into all the specialised cell types of the body when exposed to appropriate environmental cues. Adult stem cells are found in almost all tissues of the body, perhaps the best known being bone marrow, while embryonic stem cells are responsible for much of the ethical controversy that surrounds stem cells. The current therapeutic applications of stem cells include bone marrow transplantation. In the future it is likely that stem cells will be used to treat diseases of the heart, central nervous system and endocrine system among others.

Lekala leo le fetogago ka lebelo la dinyakisiso tsa stemosele le tswela pele go tsweletsa kholofelo e kgolo magareng ga balwetsi. Distemosele ke disele tsa go se farologantshwe tse di kgonago boitsosolosi bjo bo kgonago go farologantsha disele tsa go ikgetha tsa mmele go ya ka mehuta ka mo di bonagaditswe taetsong ya maleba ya tikologo. Distemosele tse di gotsego go iphetsa di nyakile go hwetswa ka ditlhalenameng tsohle tsa mmele, mohlomongwe tse di tsebjwago bokaone ke moko wa lerapo, mola distemosele tsa embrio di rwele maikarabelo a bogolo bja dingangisano mabapi le maitshwaro a distemosele. Ditiriso tsa bjale tsa terapi ya distemosele e akaretsa psalollo ya moko wa lerapo. Ka moso go ka ba le kgonagalo ya gore distemosele di somiswe go alafa malwetsi a pelo, mananeo a ditshika tsa mmele le entokirini magareng ga tse dingwe.