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Browsing Research Articles (University of Pretoria) by UP Author "Quan, Melvyn"
Now showing items 1-20 of 26
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Grewar, John Duncan; Weyer, Camilla Theresa; Guthrie, Alan John; Koen, Pieter; Davey, Sewellyn; Quan, Melvyn; Visser, Dawid; Rossouw, Esthea; Buhrmann, Gary (OpenJournals Publishing, 2013-11-15)African horse sickness (AHS) is a controlled animal disease in South Africa, and as a result of the high mortality rates experienced, outbreaks in the AHS controlled area in the Western Cape Province have a significant ...
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Weyer, Camilla Theresa; Quan, Melvyn; Joone, Christopher; Lourens, Carina W.; MacLachlan, N.J. (James); Guthrie, Alan John (Wiley-Blackwell, 2013-01)To determine whether subclinical cases, together with clinical cases, of African horse sickness (AHS) occur in immunised horses in field conditions, whole blood samples were collected and rectal temperatures recorded ...
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Banda, Frank; Sinkala, Yona; Mataa, Liywalli; Lebea, Phiyani; Sikombe, Tingiya; Kangwa, Henry L.; Fana, Elliot M.; Mokopasetso, Mokganedi; Wadsworth, Jemma; Knowles, Nick J.; King, Donald P.; Quan, Melvyn (MDPI, 2021-10)The livestock industry supports livelihood and nutritional security of at least 42% of people in the Southern African Development Community region. However, presence of animal diseases such as foot-and-mouth disease poses ...
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Woma, Timothy Yusufu; Qasim, A.M.M.; Sabi, A.A.; Abraham, M.N.; Olaiya, O.D.; Bailey, D.; Shamaki, D.; Quan, Melvyn (Wiley, 2016-06)Peste-des-petits-ruminants (PPR), a major small ruminant transboundary animal disease, is endemic in Nigeria. Strains of the causal agent, peste-des-petits-ruminants virus (PPRV), have been differentiated into four ...
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De Villiers, Lourens; Quan, Melvyn; Troskie, Milana; Jordaan, J.C. (Joyce); Leisewitz, Andrew L. (Springer, 2020-03)PURPOSE : Light microscopic manual count is the current gold standard for parasite quantification. The ability to determine parasite density in whole blood is crucial to understanding disease pathogenesis and finding a ...
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Mantip, Samuel; Quan, Melvyn; Shamaki, David; Van Vuuren, Moritz (AOSIS Open Journals, 2016-08-31)Peste-des-petits-ruminants virus (PPRV) is a highly contagious, fatal and economically important viral disease of small ruminants that is still endemic and militates against the production of sheep and goats in endemic ...
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Camarão, A.A.R.; Swanepoel, Robert; Boinas, F.; Quan, Melvyn (Elsevier, 2019-09)The Simbu serogroup within the genus Orthobunyavirus belongs to the family Peribunyaviridae and comprises 32 recognised three-segmented negative-sense single-stranded RNA viruses, with a cosmopolitan distribution. This ...
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Quan, Melvyn; Lourens, Carina W.; MacLachlan, N.J. (James); Gardner, Ian A.; Guthrie, Alan John (Elsevier, 2010)Nucleotide sequences of 52 South African isolates of African horse sickness virus (AHSV) collected during 2004–2005 and including viruses of all nine AHSV serotypes, were used to design and develop a duplex real-time ...
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Development and validation of a multiplex, real-time PCR assay for Babesia rossi and Babesia vogeli Troskie, Milana; De Villiers, Lourens; Leisewitz, Andrew L.; Oosthuizen, Marinda C.; Quan, Melvyn (Elsevier, 2019-02)Canine babesiosis is caused by tick-transmitted intraerythrocytic protozoan parasites occurring worldwide. In southern Africa, babesiosis is caused by Babesia rossi and B. vogeli and is one of the most common and important ...
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Nkosi, Nokuzola Faith; Oosthuizen, Marinda; Quan, Melvyn (Elsevier, 2022-11)Ehrlichiosis is a potentially fatal zoonotic tick-borne disease, caused by a pleomorphic Gram-negative bacterium. It occurs worldwide and affects humans, domestic and wild animals. Dogs infected with Ehrlichia canis develop ...
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Nyarku, Rejoice; Hassim, Ayesha; Jonker, Annelize; Quan, Melvyn (MDPI, 2020-11-11)The aim of this study was to develop a 16S-23S ribosomal deoxyribonucleic acid internal transcribed spacer (ITS) quantitative polymerase chain reaction (qPCR) assay for the early diagnosis and rapid screening of brucellosis. ...
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Rathogwa, Ntungufhadzeni Maclaughlin; Quan, Melvyn; Smit, J.Q.; Lourens C.; Guthrie, Alan John; Van Vuuren, Moritz (Elsevier, 2014-01)Equine encephalosis virus (EEV) is the cause of equine encephalosis. The disease is similar to mild forms of African horse sickness (AHS) and the two diseases are easily confused. Laboratory identification and serotyping ...
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Hughes, Stephen Bernard; Quan, Melvyn; Guthrie, Alan John; Schulman, M.L. (Martin) (AOSIS Open Journals, 2013-08-30)The insulin-like growth factor system (insulin-like growth factor 1, insulin-like growth factor 2, insulin-like growth factor 1 receptor, insulin-like growth factor 2 receptor and six insulinlike growth factor-binding ...
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Guthrie, Alan John; MacLachlan, N.J. (James); Joone, Christopher; Lourens, Carina W.; Weyer, Camilla Theresa; Quan, Melvyn; Monyai, Mpho S.; Gardner, Ian A. (Elsevier, 2013)Blood samples collected from 503 suspect cases of African horse sickness (AHS) and another 503 from uninfected, unvaccinated South African horses, as well as 98 samples from horses from an AHS free country, were tested ...
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Khumalo, Zamantungwa Thobeka Happiness; Brayton, Kelly A.; Collins, Nicola E.; Chaisi, Mamohale E.; Quan, Melvyn; Oosthuizen, Marinda C. (Microbiology Society, 2018-08)In 1911, Sir Arnold Theiler isolated and described a parasite that was very similar to A. marginale but which was more centrally located within the erythrocytes of the host cells, and was much less pathogenic than A. ...
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Banda, Frank; Quan, Melvyn; Shilongo, Albertina; Hikufe, Emmanuel H.; Khaiseb, Siegfried; Kabajani, Juliet; Shikongo, Beatrice; Paul, Set; Kapapero, Joseph K.; Shoombe, Kenneth K.; Zaire, Georgina; Kabilika, Swithine; Quan, Melvyn; Fana, Elliot M.; Mokopasetso, Mokganedi; Hyera, Joseph M.K.; Wadsworth, Jemma; Knowles, Nick J.; Di Nardo, Antonello; King, Donald P. (Wiley, 2022-09)This report describes the molecular characterization of a serotype O foot-and-mouth disease virus (FMDV) recovered from a field outbreak in the Zambezi region, Namibia during July 2021. Sequence analysis demonstrates ...
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Woma, Timothy Yusufu; Van Vuuren, Moritz; Bosman, Anna-Mari; Quan, Melvyn; Oosthuizen, Marinda C.; Bwala, Dauda Garba; Ibu, John O.; Ularamu, H.G. (Hussaini Gulak); Shamaki, D. (Nigerian Veterinary Medical Association, 2010)Canine distemper virus (CDV) is a highly contagious viral pathogen of worldwide distribution that can cause lethal disease in domestic dogs and other members of the family Canidae. Genetic diversity is found among reference ...
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Banda, Frank; Ludi, Anna B.; Wilsden, Ginette; Browning, Clare; Kangwa, Henry L.; Mooya, Lynnfield; Ngoma, Masuzyo; Muuka, Geoffrey M.; Mundia, Cornelius; Fandamu, Paul; Paton, David J.; King, Donald P.; Quan, Melvyn (MDPI, 2023-12-05)The recent introduction of foot-and-mouth disease (FMD) virus serotype O (O/EA-2 topotype) in Southern Africa has changed the epidemiology of the disease and vaccine requirements of the region. Commercial and subsistence ...
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Akwongo, Claire Julie; Quan, Melvyn; Byaruhanga, Charles (MDPI, 2022-01-02)Peste des petits ruminants (PPR), a disease caused by small ruminant morbillivirus (SRM), is highly contagious with high morbidity and mortality. Controlling PPR requires a proper understanding of the epidemiological ...
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Guthrie, Alan John; Quan, Melvyn; Lourens, Carina W.; Audonnet, Jean-Christophe; Minke, Jules M.; Yao, Jiansheng; He, Ling; Nordgren, Robert; Gardner, Ian A.; MacLachlan, N.J. (James) (Elsevier, 2009-07)We describe the development and preliminary characterization of a recombinant canarypox virus vectored (ALVAC®) vaccine for protective immunization of equids against African horse sickness virus (AHSV) infection. Horses ...
Now showing items 1-20 of 26