Screening of Venda medicinal plants for antifungal activity against Candida albicans

dc.contributor.authorFernandes, Anthony C.
dc.contributor.emailvsteen@med.up.ac.zaen
dc.contributor.upauthorJansen van Rensburg, Connie E.
dc.contributor.upauthorSteenkamp, Vanessa
dc.date.accessioned2008-06-02T07:55:39Z
dc.date.available2008-06-02T07:55:39Z
dc.date.issued2007-04
dc.description.abstractCrude methanol and water extracts of 32 plant species, used for the treatment of infectious diseases in Venda, were screened for in vitro activity against Candida albicans standard strain (ATCC 10231) and five clinical isolates. Water extracts of 16 plant species and methanol extracts of 11 plant species inhibited candidiasis growth. Inhibition at < 1 mg/ml, against the C. albicans strains tested, was observed for the methanol extracts of Combretum molle (root), Piper capense (bark), Solanum aculeastrum (fruits), Syzygium cordatum (bark) and Zanthoxylum davyi (bark) as well as the aqueous bark extract of Afzelia quanzensis and root extract of Tabernaemontana elegans. These results implicate that the extracts contain compounds with therapeutic potential against C. albicans.en
dc.description.sponsorshipNational Research Foundationen
dc.format.extent187277 bytes
dc.format.mimetypeapplication/pdf
dc.identifier.citationSteenkamp, V, Fernandes, AC & Van Rensburg, CEJ 2007, 'Screening of Venda medicinal plants for antifungal activity against Candida albicans', South African Journal of Botany, vol. 73, no. 2, pp. 256-258. [http://www.sciencedirect.com/science/journal/02546299]en
dc.identifier.issn0254-6299
dc.identifier.other10.1016/j.sajb.2006.11.003
dc.identifier.urihttp://hdl.handle.net/2263/5745
dc.language.isoenen
dc.publisherElsevieren
dc.rightsElsevieren
dc.subjectAntifungal activityen
dc.subjectCandida albicansen
dc.subjectTraditional medicineen
dc.subjectVendaen
dc.subject.lcshMedicinal plants
dc.subject.lcshVenda (African people)
dc.subject.lcshCandida albicans -- Therapeutics
dc.subject.lcshSyzygium cordatum
dc.subject.lcshAntifungal agents
dc.subject.lcshMethanol -- Extracts
dc.titleScreening of Venda medicinal plants for antifungal activity against Candida albicansen
dc.typePostprint Articleen

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