School and community driven dengue vector control and monitoring in Myanmar : study protocol for a cluster randomized controlled trial

dc.contributor.authorOvergaard, Hans J.
dc.contributor.authorLinn, Nay Yi Yi
dc.contributor.authorKyaw, Aye Mon Mon
dc.contributor.authorBraack, L.E.O.
dc.contributor.authorTin, Myo Win
dc.contributor.authorBastien, Sheri
dc.contributor.authorVelde, Fiona Vande
dc.contributor.authorEchaubard, Pierre
dc.contributor.authorZaw, Win
dc.contributor.authorMukaka, Mavuto
dc.contributor.authorMaude, Richard
dc.date.accessioned2024-04-16T05:41:15Z
dc.date.available2024-04-16T05:41:15Z
dc.date.issued2023-08
dc.descriptionDATA AVAILABILITY : No data are associated with this article.en_US
dc.description.abstractBACKGROUND : Dengue is the most common and widespread mosquito-borne arboviral disease globally estimated to cause >390 million infections and >20,000 deaths annually. There are no effective preventive drugs and the newly introduced vaccines are not yet available. Control of dengue transmission still relies primarily on mosquito vector control. Although most vector control methods currently used by national dengue control programs may temporarily reduce mosquito populations, there is little evidence that they affect transmission. There is an urgent need for innovative, participatory, effective, and locally adapted approaches for sustainable vector control and monitoring in which students can be particularly relevant contributors and to demonstrate a clear link between vector reduction and dengue transmission reduction, using tools that are inexpensive and easy to use by local communities in a sustainable manner. METHODS : Here we describe a cluster randomized controlled trial to be conducted in 46 school catchment areas in two townships in Yangon, Myanmar. The outcome measures are dengue cases confirmed by rapid diagnostic test in the townships, dengue incidence in schools, entomological indices, knowledge, attitudes and practice, behavior, and engagement. CONCLUSIONS : The trial involves middle school students that positions them to become actors in dengue knowledge transfer to their communities and take a leadership role in the delivery of vector control interventions and monitoring methods. Following this rationale, we believe that students can become change agents of decentralized vector surveillance and sustainable disease control in line with recent new paradigms in integrated and participatory vector surveillance and control. This provides an opportunity to operationalize transdisciplinary research towards sustainable health development. Due to the COVID-19 pandemic and political instability in Myanmar the project has been terminated by the donor, but the protocol will be helpful for potential future implementation of the project in Myanmar and/or elsewhere. REGISTRATION : This trial was registered in the ISRCTN Registry on 31 May 2022 (https://doi.org/10.1186/ISRCTN78254298).en_US
dc.description.departmentMedical Virologyen_US
dc.description.librarianam2024en_US
dc.description.sdgSDG-03:Good heatlh and well-beingen_US
dc.description.sponsorshipThis work was supported by Wellcome [Grant number 220211]; The Research Council of Norway (RCN, GLOBVAC project no. 285188); the Norwegian University of Life Sciences and the Malaria Consortium. The funding bodies did not have any role in project design or in the writing of the manuscript. Trial sponsor is the Norwegian University of Life Sciences. For the purpose of open access, the author has applied a CC BY public copyright license to any Author Accepted Manuscript version arising from this submission. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.en_US
dc.description.sponsorshipWellcome Trust; The Research Council of Norway; the Norwegian University of Life Sciences and the Malaria Consortium.en_US
dc.description.urihttps://wellcomeopenresearch.orgen_US
dc.identifier.citationOvergaard, H.J., Linn, N.Y.Y., Kyaw, A.M.M. et al. School and community driven dengue vector control and monitoring in Myanmar: Study protocol for a cluster randomized controlled trial. Wellcome Open Research 2023, 7:206 .https://DOI.org/10.12688/wellcomeopenres.18027.2.en_US
dc.identifier.issn2398-502X
dc.identifier.other10.12688/wellcomeopenres.18027.2
dc.identifier.urihttp://hdl.handle.net/2263/95548
dc.language.isoenen_US
dc.publisherTaylor and Francisen_US
dc.rights© 2023 Overgaard HJ et al. This is an open access article distributed under the terms of the Creative Commons Attribution License.en_US
dc.subjectSchoolen_US
dc.subjectKnowledge, attitudes, and practice (KAP)en_US
dc.subjectCommunity engagementen_US
dc.subjectImplementation fidelityen_US
dc.subjectAedesen_US
dc.subjectMosquito-borne arboviral diseaseen_US
dc.subjectDengueen_US
dc.subjectSDG-03: Good health and well-beingen_US
dc.titleSchool and community driven dengue vector control and monitoring in Myanmar : study protocol for a cluster randomized controlled trialen_US
dc.typeArticleen_US

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Overgaard_School_2023.pdf
Size:
2.32 MB
Format:
Adobe Portable Document Format
Description:
Article

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description: