Dr Spur's mystery case : Is the answer in the gut?

dc.contributor.authorVan den Berg, Sylvia
dc.contributor.authorBrauer, Marieke
dc.contributor.authorVan Niekerk, Andre
dc.contributor.emailandre.vanniekerk@up.ac.za
dc.date.accessioned2025-05-28T12:44:39Z
dc.date.available2025-05-28T12:44:39Z
dc.date.issued2024-06-01
dc.description.abstractI have been treating a delightful young 16-year-old lady for a couple of years now in my practice. She has been diagnosed with selective IgA deficiency when she was six years old, after suffering from more than the usual amount of upper respiratory infections in comparison with her peers. She is also atopic suffering from allergic rhinitis and is sensitised to grasses. Unfortunately, she also developed type 1 Diabetes Mellitus when she was eight years old. Despite all her afflictions, she has a sunny disposition and is a very brave girl. I have come across articles where it is stated that IgA is particularly important in maintaining microbiome homeostasis. Can all her symptoms be contributed to a microbial dysbiosis? How can I manage her more optimally? Your opinion and guidance in this matter will be highly appreciated.
dc.description.departmentPaediatrics and Child Health
dc.description.librarianom2025
dc.description.sdgSDG-03: Good health and well-being
dc.description.urihttps://journals.co.za/journal/caci
dc.identifier.citationVan den Berg, S., Brauer, M. & Van Niekerk, A. 2024, 'Dr Spur's mystery case : is the answer in the gut?', Current Allergy and Clinical Immunology, vol. 37, no. 2, pp. 107-111, doi : 10.10520/ejc-caci-v37-n2-a12.
dc.identifier.issn1609-3607 (print)
dc.identifier.other10.10520/ejc-caci-v37-n2-a12
dc.identifier.urihttp://hdl.handle.net/2263/102568
dc.language.isoen
dc.publisherAllergy Society of South Africa
dc.rights© 2024. Allergy Society of South Africa (ALLSA). This work is licensed under a Creative Commons Attribution-Non Commercial-Share Alike 4.0 International License.
dc.subjectSelective IgA deficiency (sIgAD)
dc.subjectGut microbiome
dc.subjectMicrobial dysbiosis
dc.subjectImmune homeostasis
dc.subjectAutoimmune disorders
dc.titleDr Spur's mystery case : Is the answer in the gut?
dc.typeArticle

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