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Browsing University of Pretoria: Research Output by UP Author "Page, Nicola Anne"
Now showing items 1-20 of 23
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Schubert, Grit; Achi, Vincent; Ahuka, Steve; Belarbi, Essia; Bourhaima, Ouattara; Eckmanns, Tim; Johnstone, Siobhan L.; Kabore, Firmin; Kra, Ouffoue; Mendes, Adriano; Ouedraogo, Abdoul-Salam; Poda, Armel; Some, Arsene Satouro; Tomczyk, Sara; Couacy-Hymann, Emmanuel; Kayembe, Jean-Marie; Meda, Nicolas; Tamfum, Jean-Jacques Muyembe; Ouangraoua, Soumeya; Page, Nicola Anne; Venter, Marietjie; Leendertz, Fabian H.; Akoua-Koffi, Chantal (BioMed Central, 2021-06-07)BACKGROUND : In sub-Saharan Africa, acute respiratory infections (ARI), acute gastrointestinal infections (GI) and acute febrile disease of unknown cause (AFDUC) have a large disease burden, especially among children, ...
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Fellows, Tamika; Page, Nicola Anne; Fix, Alan; Flores, Jorge; Cryz, Stanley; McNeal, Monica; Iturriza-Gomara, Miren; Groome, Michelle J. (MDPI, 2023-08-25)A correlate of protection for rotavirus (RV) has not been consistently identified. Shedding of RV following an oral rotavirus vaccine (ORV) challenge has been investigated as a potential model to assess protection of ...
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Davids, Michaela; Johnstone, Siobhan; Mendes, Adriano; Brecht, Gadean; Avenant, Theunis Johannes; Du Plessis, Nicolette Marie; De Villiers, Maryke; Page, N.A. (Nicola); Venter, Marietjie (MDPI, 2024-03)Severe acute respiratory tract infections (SARIs) has been well described in South Africa with seasonal patterns described for influenza and respiratory syncytial virus (RSV), while others occur year-round (rhinovirus and ...
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Nadan, Sandrama; Taylor, Maureen B.; Page, Nicola Anne (Elsevier, 2021-02)BACKGROUND : Astroviruses (AstVs) are associated with diarrhoeal and extra-intestinal infections in human, animal and avian species. A prevalence of 7% was reported in selected regions in SA while AstVs detected from ...
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Johnstone, Siobhan; Page, Nicola Anne; Groome, Michelle J.; Du Plessis, Nicolette Marie; Thomas, Juno (BMC, 2022-11-09)BACKGROUND : Stool samples submitted for diagnostic testing represent a proportion of diarrhoeal cases seeking healthcare, and an even smaller proportion of diarrhoeal cases in the community. Despite this, surveillance ...
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Johnstone, Siobhan L.; Page, Nicola Anne; Thomas, Juno; Madhi, Shabir A.; Mutevedzi, Portia; Myburgh, Nellie; Herrera, Carlos; Groome, Michelle J. (BioMed Central, 2021-07-20)BACKGROUND : In South Africa, there are limited data on the burden of diarrhoea at a community level, specifically in older children and adults. This community survey estimated rates of and factors associated with diarrhoea ...
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Mohy, Ahmed; Page, N.A. (Nicola); Boyce, Welekazi; Gomez, Jorge A. (Springer, 2023-11)BACKGROUND AND OBJECTIVE Evidence on the economic value of rotavirus vaccines in middle-income countries is limited. We aimed to model the implementation of three vaccines (human rotavirus, live, attenuated, oral vaccine ...
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Nadan, Sandrama; Taylor, Maureen B.; Groome, Michelle J.; Cohen, Cheryl; Madhi, Shabir A.; Page, Nicola Anne (Wiley, 2019-02)BACKGROUND : The epidemiology of human astroviruses (HAstVs) in hospitalised patients less than 5 years of age from selected sites in South Africa was investigated. Diarrheagenic stool specimens collected from April 2009 ...
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Mwangi, Peter N.; Page, Nicola Anne; Seheri, Mapaseka L.; Mphahlele, M.; Nadan, Sandrama; Esona, Mathew D.; Kumwenda, Benjamin; Kamng’ona, Arox W.; Donato, Celeste M.; Steele, Duncan A.; Ndze, Valantine N.; Dennis, Francis E.; Jere, Khuzwayo C.; Nyaga, Martin M. (Microbiology Society, 2022-04)The transient upsurge of G2P[4] group A rotavirus (RVA) after Rotarix vaccine introduction in several countries has been a matter of concern. To gain insight into the diversity and evolution of G2P[4] strains in South ...
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MacDonald, Jaime Claire; Groome, Michelle J.; Janet, Janet; Page, Nicola Anne (MDPI, 2020-09)Gastroenteritis is a preventable cause of morbidity and mortality worldwide. Rotavirus vaccination has significantly reduced the disease burden, but the sub-optimal vaccine efficacy observed in low-income regions needs ...
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Johnstone, Siobhan L.; Page, Nicola Anne; Groome, Michelle J.; Madhi, Shabir A.; Mutevedzi, Portia; Thomas, Juno (AOSIS, 2022-03-31)Effective risk communication is essential for outbreak mitigation, as recently highlighted during the coronavirus disease 2019 (COVID-19) pandemic. Hand hygiene is one of the proposed public health interventions to protect ...
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Shonhiwa, Andronica Moipone; Ntshoe, Genevie M.; Crisp, Noreen; Olowolagba, Ayo J.; Mbuthu, Vusi; Taylor, Maureen B.; Thomas, Juno; Page, Nicola Anne (AOSIS, 2020-07-22)BACKGROUND : Suspected diarrhoeal-illness outbreaks affecting mostly children < 5 years were investigated between May and July 2013 in Northern Cape province (NCP) and KwaZulu-Natal (KZN) province. This study describes ...
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Page, N.A. (Nicola); Netshikweta, Rembuluwani; Tate, Jacqueline E.; Madhi, Shabir A.; Parashar, Umesh D.; Groome, Michelle J. (Oxford University Press, 2023-09)A matched case-control evaluated infectious etiologies in children <3 years in post-rotavirus vaccine intussusception surveillance. Adenovirus and adenovirus types C, A, and B were detected more frequently in cases versus ...
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Netshikweta, Rembuluwani; Chidamba, Lizyben; Nadan, Sandrama; Taylor, Maureen B.; Page, Nicola Anne (Wiley, 2020-08)Human bocavirus (HBoV) is known to be associated with a variety of clinical manifestation including acute gastroenteritis (AGE). Despite their global prevalence, no data is available on the epidemiology of HBoV associated ...
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Page, Nicola Anne; Groome, M.J.; Nadan, Sandrama; Netshikweta, Rembuluwani; Keddy, Karen H.; Poonsamy, B.; Moyes, J.; Walaza, Sibongile; Kahn, K.; Madhi, S.A.; Taylor, Maureen B.; Mans, Janet; Cohen, C. (Cambridge University Press , 2017-07)Public health interest in norovirus (NoV) has increased in recent years following improved diagnostics, global burden estimates and the development of NoV vaccine candidates. This study aimed to describe the detection rate, ...
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Thomas, J.; Govender, N.; McCarthy, K.M.; Erasmus, L.K.; Doyle, T.J.; Allam, M.; Ismail, A.; Ramalwa, Ntsieni; Sekwadi, P.; Ntshoe, Genevie M.; Shonhiwa, A.; Essel, V.; Tau, N.; Smouse, S.; Ngomane, H.M.; Disenyeng, B.; Page, Nicola Anne; Govender, N.P.; Duse, A.G.; Stewart, R.; Thomas, T.; Mahoney, D.; Tourdjman, M.; Disson, O.; Thouvenot, P.; Maury, M.M.; Leclercq, A.; Lecuit, M.; Smith, Anthony M.; Blumberg, Lucille Hellen (http://content.nejm.org/, 2020-02)BACKGROUND: An outbreak of listeriosis was identified in South Africa in 2017. The source was unknown. METHODS: We conducted epidemiologic, trace-back, and environmental investigations and used whole-genome sequencing ...
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Joao, Eva Dora; Strydom, Amy; O’Neill, Hester G.; Cuamba, Assa; Cassocera, Marta; Acacio, Sozinho; Mandomando, Inacio; Motanyane, Lithabiso; Page, Nicola Anne; De Deus, Nilsa (Springer Verlag, 2018-01)In Mozambique rotavirus (RV) was shown to be the greatest cause of acute diarrhoea in infants from 0 to 11 months, and in 2015, national rotavirus vaccination was introduced. As with other developing countries, there is ...
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Groome, Michelle J.; Koen, Anthonet; Fix, Alan; Page, Nicola Anne; Jose, Lisa; Madhi, Shabir A.; McNeal, Monica; Dally, Len; Cho, Iksung; Power, Maureen; Flores, Jorge; Cryz, Stanley (Elsevier, 2017-08)BACKGROUND Efficacy of live oral rotavirus vaccines is reduced in low-income compared with high-income settings. Parenteral non-replicating rotavirus vaccines might offer benefits over oral vaccines. We assessed the ...
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Groome, Michelle J.; Fairlie, Lee; Morrison, Julie; Fix, Alan; Koen, Anthonet; Masenya, Maysseb; Jose, Lisa; Madhi, Shabir A.; Page, Nicola Anne; McNeal, Monica; Dally, Len; Cho, Iksung; Power, Maureen; Flores, Jorge; Cryz, Stanley (Elsevier, 2020-07)BACKGROUND : A monovalent, parenteral, subunit rotavirus vaccine was well tolerated and immunogenic in adults in the USA and in toddlers and infants in South Africa, but elicited poor responses against heterotypic rotavirus ...
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Page, Nicola Anne; Groome, Michelle J.; Murray, Tanya Y.; Nadan, Sandrama; Netshikweta, Rembuluwani; Keddy, Karen H.; Poonsamy, Bhavani; Moyes, Jocelyn; Walaza, Sibongile; Kahn, Kathleen; Kuonza, Lazarus R.; Taylor, Maureen B.; Madhi, Shabir A.; Cohen, Cheryl (Elsevier, 2016-05)BACKGROUND : Although sapovirus (SaV) has been detected in 2.2–12.7% of gastroenteritis cases globally,there are limited data on SaV epidemiology. OBJECTIVES : Describe the epidemiology, clinical characteristics and factors ...
Now showing items 1-20 of 23