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Neurology: Recent submissions
Now showing items 21-40 of 45
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(BMJ Publishing Group, 2017)Mitochondrial neurogastrointestinal encephalopathy (MNGIE), usually an autosomal-recessive inherited condition, causes gastrointestinal dysmotility, ophthalmoplegia, ptosis, leukoencephalopathy and neuropathy. The chromosome ...
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(Elsevier, 2016-01)The diagnosis of porphyria remains challenging as the condition is characterized by a myriad of clinical and biochemical features. More importantly, an acute attack is associated with increased morbidity and mortality. ...
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(Sage, 2017-06)AIM : This retrospective cohort study analyzes the impact of possible risk factors on the survival chance of patients with cryptococcal meningitis. These factors include the patient's socio-economic background, age, gender, ...
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(Springer, 2011-05)Stroke is one of the leading causes of death worldwide. Formation of a fibrin clot is controlled by a group of tightly regulated plasma proteases and cofactors and a change in the fibrin fiber formation causes an alteration ...
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(Health and Medical Publishing Group, 2016-06)BACKGROUND. Parkinson’s disease (PD), with a prevalence of up to 4% in Western countries, appears to be less common in Africa, possibly in part because of genetic factors. African studies investigating the genetic causation ...
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(Health and Medical Publishing Group, 2016-01)The hepatic porphyrias are a group of rare metabolic disorders, each of which is associated with a specific enzymatic alteration in the haem biosynthesis pathway. In South Africa (SA), a high incidence of variegate porphyria ...
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(BioMed Central, 2015)BACKGROUND : Strokes are commonly preceded by transient ischemic attacks (TIAs). TIA is often associated with metabolic syndrome (causing chronic inflammation), resulting in a proinflammatory- and procoagulantenvironment. The ...
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(Health and Medical Publishing Group, 2015-06-26)We report the case of an HIV-positive female patient with neurofibromatosis type 1 who was treated for recurrent peptic ulcer disease and later developed diabetes mellitus and chronic diarrhoea. A metastasising somatostatinoma ...
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(Health and Medical Publishing Group, 2015-07)Autosomal dominantly inherited oculopharyngeal muscular dystrophy (OPMD) is caused by a trinucleotide repeat expansion in exon 1 of the polyadenylate binding protein nuclear 1 (PABPN1) gene on chromosome 14q. A large ...
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(Karger, 2014-10)Paroxysmal nonkinesigenic dyskinesia (PNKD) causes episodes of treatment-resistant involuntary movements. Previous case reports showed effective treatment of PNKD with deep brain stimulation (DBS). We report 2 patients in ...
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(MedPharm Publications, 2015)Inhalation of volatile agents, or solvent abuse, is a dangerous pastime practised by many young adolescents in various parts of the world. Benzine, a distillate of petroleum, is a cheap and readily available solvent that ...
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(Impact Journals, 2014-10)A major trend in recent Parkinson’s disease (PD) research is the investigation of biological markers that could help in identifying at‐risk individuals or to track disease progression and response to therapies. Central ...
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(Health and Medical Publishing Group, 2014-06)Neurodegenerative diseases are important causes of disability and death, with prominent examples including Alzheimer’s disease, Parkinson’s disease (PD) and motor neuron disease. Although familial clustering of these ...
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(Springer, 2014-08)Berichtet wird über eine 63 jährige Patientin mit Diabetes mellitus und einer unilateralen Hemichorea-Athetose, bei der eine nicht-ketotische Hyperglykämie als Ursache diagnostiziert wurde. Diese seltene Komplikation im ...
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(Health and Medical Publishing Group, 2013-01)BACKGROUND. HTLV-1 associated myelopathy (HAM), or tropical spastic paraparesis, is caused by a retrovirus, the human T-cell lymphotropic virus (HTLV). Although patients with HAM and HIV infection have been described, to ...
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(Health and Medical Publishing Group, 2013-06)INTRODUCTION AND OBJECTIVES: Progressive multifocal leukoencephalopathy (PML), caused by the John Cunningham (JC) virus, results from lytic infection of predominantly oligodendrocytes. Following the HIV pandemic, the ...
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(Health and Medical Publishing Group, 2013-11)BACKGROUND. South Africa (SA) has a high prevalence of HIV infection with almost 11% of the population aged >2 years living with HIV. At the Steve Biko Academic Hospital, Pretoria, the Neurology Department has seen a steady ...
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(University of Pretoria, 2012-05-08)Cysticercosis is emerging as a serious public health and agricultural problem in countries of Eastern and Southern Africa (ESA). Caused by a pork tapeworm, this zoonotic disease forms cysts in the tissues of pigs and ...
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(University of Pretoria, 2005-10-28)Meningitis remains a frightening disease with a high morbidity and mortality in spite of optimal treatment. In South Africa in particular, the incidence of HIV-infected patents with meningitis has risen considerably during ...
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The outcome of intracranial subdural empyema at Steve Biko Academic Hospital : retrospective study (University of Pretoria, 2013-01-15)Objectives: Intracranial subdural empyema (ICSDE) can be a devastating condition, with a sequelae ranging from epilepsy, focal deficits to death. Factors affecting the outcome in subdural empyema range from level of ...
Now showing items 21-40 of 45