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Browsing Surgery by UP Author "Brand, Martin"
Now showing items 1-18 of 18
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Govener, T.; Brand, Martin (In House Publications, 2022)Acute pancreatitis refers to acute inflammation of the pancreas, usually accompanied by abdominal pain and elevations of serum pancreatic enzymes. This syndrome is usually a discrete episode which causes varying degrees ...
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Brand, Martin (In House Publications, 2022)Chronic calcific pancreatitis (CP) is a progressive fibro-inflammatory disease of the pancreas. In its later stages it is characterized by both exocrine dysfunction presenting as malabsorption and steatorrhea, and endocrine ...
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Brand, Martin; Gaylard, P.; Ramos, J. (Health and Medical Publishing Group, 2018-02)BACKGROUND. Colorectal cancer (CRC) is the fourth most common cancer in South Africa (SA), and the sixth most lethal. Approximately 25% of patients will have synchronous metastatic disease at the time of their primary CRC ...
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Brand, Martin; Gaylard, P.; Ramos, J. (South African Medical Association, 2021-03)BACKGROUND : Approximately 25% of patients with colorectal cancer (CRC) will be diagnosed with CRC liver metastases (CRCLM) during the course of their disease. No data regarding CRCLM presentation, management and survival ...
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Elsenbroek, Christiaan F.; Brand, Martin (Sage, 2023-04)BACKGROUND : Colorectal anastomotic leaks remain one of the most significant complications following colorectal surgery. Various interventions to reduce anastomotic leaks have been investigated, however few have resulted ...
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Nweke, Ekene Emmanuel; Brand, Martin (Spandidos, 2020)Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer type characterized by dysregulated cell signalling pathways and resistance to treatment. The insulin‑like growth factor (IGF) signalling pathway has been ...
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Jonas, Eduard; Brand, Martin (Medpharm Publications, 2023)No abstract available.
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Van Waart, J.; Matley, P.J.; Brand, Martin (Health and Medical Publishing Group, 2020-06)Since the introduction of a national state of disaster at the end of March 2020 we have moved through levels of “lockdown” and as of 1 June 2020 it has been de-escalated to level 3. It is unclear as to how long this ...
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Thomson, John-Edwin; Brand, Martin; Fonteh, Pascaline (Elsevier, 2018-04)BACKGROUND : Severe acute pancreatitis (SAP) is characterised by two distinct clinical phases. Organ dysfunction and death is initially as a result of a systemic inflammatory response syndrome (SIRS). Systemic sepsis from ...
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Nweke, Ekene Emmanuel; Ntwasa, Monde; Brand, Martin; Devar, John; Smith, Martin; Candy, Geoffrey (Spandidos, 2020-06)Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancer types, and it is associated with a 5‑year survival rate of <10% due to limited early detection methods and ineffective therapeutic options. Thus, an ...
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Khan, Zafar Ahmed; Khan, Muhammed Uzayr; Brand, Martin (Nature Publishing Group, 2020-08-11)Studies suggest that the rate gallstone disease in Africa is low. Previous studies suggested an increase in gallstone rates and cholecystectomies related to urbanization and the adoption of Western lifestyle habits. This ...
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Thomson, John-Edwin; Van Dijk, Sven M.; Brand, Martin; Van Santvoort, Hjalmar C.; Besselink, Marc G. (Editura Celsius, 2018-05)Managementul necrozei pancreatice infectate a început cu necrozecto-mia deschisă precoce, asociată cu o mortalitate semnificativă. În ultimii ani, a avut loc o transformare bazată pe dovezi înspre abordarea progresivă ...
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Mauser, Martin; Bartsokas, Christos; Brand, Martin; Plani, Frank (Elsevier, 2019-01)INTRODUCTION : The influence of trauma- and surgical stress-induced decrease of CD4 count on anastomotic leaks after penetrating abdominal trauma has to date not been investigated. A prospective study was performed to ...
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Brand, Martin; Grieve, Andrew (Wiley, 2019-12)BACKGROUND : Penetrating abdominal trauma occurs when the peritoneal cavity is breached. Routine laparotomy for penetrating abdominal injuries began in the 1800s, with antibiotics first being used in World War II to ...
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Ede, Chikwendu J.; Ede, Roseline; Brand, Martin (Wiley, 2019-11)This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the benefits and harms of any type of selective shunt versus any type of non-selective shunt for the prevention of ...
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Ede, Chikwendu J; Nikolova, Dimitrinka; Brand, Martin (Wiley, 2018-08)BACKGROUND: Hepatosplenic schistosomiasis is an important cause of variceal bleeding in low-income countries. Randomised clinical trials have evaluated the outcomes of two categories of surgical interventions, shunts and ...
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Brand, Martin; Prodehl, L.; Ede, Chikwendu J. (Wiley, 2018-10-31)BACKGROUND : Variceal haemorrhage that is refractory or recurs after pharmacologic and endoscopic therapy requires a portal decompression shunt (either surgical shunts or radiologic shunt, transjugular intrahepatic ...
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Thomson, John-Edwin; Nweke, Ekene Emmanuel; Brand, Martin; Nel, Marietha; Candy, Geoffrey P.; Fonteh, Pascaline N. (Lippincott, Williams and Wilkins, 2019-01)OBJECTIVES : Interleukin-21 (IL-21) is a cytokine associated with tissue inflammation, autoimmune and infectious diseases. Organ dysfunction and death can occur in patients with acute pancreatitis (AP) in two distinct ...
Now showing items 1-18 of 18