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Browsing Surgery by Subject "Acute pancreatitis (AP)"

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The immune imbalance in the second hit of pancreatitis is independent of IL-17A

Thomson, John-Edwin; Brand, Martin; Fonteh, Pascaline (Elsevier, 2018-04)

BACKGROUND : Severe acute pancreatitis (SAP) is characterised by two distinct clinical phases. Organ dysfunction and death is initially as a result of a systemic inflammatory response syndrome (SIRS). Systemic sepsis from ...
Transient expression of Interleukin-21 in the second hit of acute pancreatitis may potentiate immune paresis in severe acute pancreatitis

Thomson, John-Edwin; Nweke, Ekene Emmanuel; Brand, Martin; Nel, Marietha; Candy, Geoffrey P.; Fonteh, Pascaline N. (Lippincott, Williams and Wilkins, 2019-01)

OBJECTIVES : Interleukin-21 (IL-21) is a cytokine associated with tissue inflammation, autoimmune and infectious diseases. Organ dysfunction and death can occur in patients with acute pancreatitis (AP) in two distinct ...

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