Browsing Surgery by Title

Browsing Surgery by Title

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  • Gastro-intestinal stromal tumours (GISTs) – the Pretoria experience and a literature review 
    Hartley, R.J.; Becker, J.H.R. (Hennie); Van der Walt, Hannes; Luvhengo, T. (Health and Medical Publishing Group, 2011-08)
    AIM: To analyse the presentation and management of patients with gastro-intestinal stromal tumours (GISTs) at Pretoria hospitals. DESIGN: A retrospective study was done in which all available clinical records of primary ...
  • Genetic drivers of head and neck squamous cell carcinoma : aberrant splicing events, mutational burden, hpv infection and future targets 
    Dlamini, Zodwa; Alaouna, Mohammed; Mbatha, Sikhumbuzo Z.; Bhayat, Ahmed; Mabongo, Mzubanzi; Chatziioannou, Aristotelis; Hull, Rodney (MDPI, 2021-03-15)
    Head and neck cancers include cancers that originate from a variety of locations. These include the mouth, nasal cavity, throat, sinuses, and salivary glands. These cancers are the sixth most diagnosed cancers worldwide. ...
  • Genomic interplay between neoneurogenesis and neoangiogenesis in carcinogenesis : therapeutic interventions 
    Dlamini, Zodwa; Khanyile, Richard; Molefi, Thulo; Damane, Botle Precious; Bates, David Owen; Hull, Rodney (MDPI, 2023-03-16)
    Angiogenesis, the generation of new blood vessels, is one of the hallmarks of cancer. The growing tumor requires nutrients and oxygen. Recent evidence has shown that tumors release signals to attract new nerve fibers and ...
  • Glycaemic control in a cardiothoracic surgical population : exploring the protocol-practice gap 
    Maharaj, D.; Perrie, H.; Scribante, J.; Paruk, Fathima (Health and Medical Publishing Group, 2017-07)
    BACKGROUND : Glycaemic control constitutes an important component in the management of critically ill patients. As such, all healthcare workers involved in the management of critically ill patients need to ensure that ...
  • Guideline : Appropriate use of tigecycline 
    Brink, Andries J.; Bizos, D.; Boffard, Kenneth D.; Feldman, Charles; Grolman, D.C.; Pretorius, Jan P.; Richards, Guy A.; Senekal, M.; Steyn, E.; Welkovic, N. (Health and Medical Publishing Group, 2010-06)
    INTRODUCTION: Tigecycline, the first of a new class of antibiotics, the glycylcyclines, was licensed in South Africa for the parenteral treatment of adult patients with complicated intraabdominal infections (cIAIs) and ...
  • Guideline summary : appropriate use of tigecycline 
    Brink, Adrian J.; Bizos, D.; Boffard, Kenneth D.; Feldman, Charles; Grolman, D.C.; Pretorius, J.; Richards, Guy A.; Steyn, E. (Health and Medical Publishing Group, 2012-02)
    Tigecycline, the first of a new class of broad-spectrum antibiotics (the glycylcyclines), has been licensed in South Africa for the parenteral treatment of adult patients with complicated intra-abdominal infections (cIAIs) ...
  • Herbert Otto Penzhorn (14 April 1944 - 23 February 2011) 
    Mieny, Carel J. (Health and Medical Publishing Group, 2011-08)
    It was with shock, if not total disbelief, that the surgical community in Pretoria learned of the untimely death of our colleague Herbie Penzhorn on the morning of 23 February 2011. He was killed by crocodiles on his farm ...
  • The histology of peau d’orange in breast cancer : what are the implications for surgery? 
    Wiggett, W.S.; Louw, Melanie; Karusseit, V.O.L. (Otto) (Health and Medical Publishing Group, 2012-08)
    INTRODUCTION: Surgery is sometimes performed on patients with peau d'orange (dermal oedema) of the breast. This may be done to achieve local control of cancer after neo-adjuvant chemotherapy or in resectable locally advanced ...
  • HIV-associated vasculopathy 
    Mulaudzi, Thanyani Victor (Health and Medical Publishing Group, 2009-07)
    Human immunodeficiency virus (HIV) disease was first described in 1981 in the USA in young homosexual men presenting with opportunistic infections associated with severe immune deficiency. The virus itself was identified ...
  • HIV-occlusive vascular disease 
    Van Marle, J.; Mistry, P.P.; Botes, K. (Health and Medical Publishing Group, 2009-05)
    OBJECTIVES: To evaluate peripheral arterial occlusive disease in HIV-infected patients regarding clinical presentation and outcome of surgical intervention. DESIGN: Prospective clinical survey. PATIENTS AND METHODS: ...
  • Hypercoagulability using biophysical parameters in HIV positive versus HIV negative patients with deep vein thrombosis 
    Jackson, Brandon Spencer (University of Pretoria, 2018)
    Introduction: Patients infected with the Human immunodeficiency virus (HIV) are more prone to developing a hypercoagulable state. This may be due an upregulated inflammatory system resulting in a different coagulation ...
  • The immune imbalance in the second hit of pancreatitis is independent of IL-17A 
    Thomson, John-Edwin; Brand, Martin; Fonteh, Pascaline (Elsevier, 2018-04)
    BACKGROUND : Severe acute pancreatitis (SAP) is characterised by two distinct clinical phases. Organ dysfunction and death is initially as a result of a systemic inflammatory response syndrome (SIRS). Systemic sepsis from ...
  • The impact of colon injuries on the outcome of gunshot wounds to the abdomen 
    Singh, Yonita; Motilall, Sooraj; Khulu, Bongani L.; Jackson, Brandon Spencer (Springer, 2023-08)
    PURPOSE : Factors predicting morbidity and mortality in patients with colon-related gunshot injuries and the management of these injuries are not always straightforward. This aimed to assess the impact of abdominal gunshot ...
  • Improved understanding of the pathophysiology of sepsis : setting the scene for potential novel adjunctive therapies 
    Chausse, J.M.; Malekele, L.; Paruk, Fathima (Health and Medical Publishing Group, 2018)
    The occurrence of sepsis in the critically ill population is a dreaded phenomenon when taking into consideration the devastating complications associated with the disease. Despite its high incidence and unacceptably high ...
  • The incidence of malignancy in neoplasms of the submandibular salivary gland 
    Schoeman, Bernardus Johannes; Clifford, S.D. (Health and Medical Publishing Group, 2007-11)
    OBJECTIVE: To test the validity of the reported high incidence (50%) of malignancy in neoplasms of the submandibular salivary gland, and to compare it with that of the parotid gland. METHODS: This is a retrospective ...
  • Increased expression of plakoglobin is associated with upregulated MAPK and PI3K/AKT signalling pathways in early resectable pancreatic ductal adenocarcinoma 
    Nweke, Ekene Emmanuel; Ntwasa, Monde; Brand, Martin; Devar, John; Smith, Martin; Candy, Geoffrey (Spandidos, 2020-06)
    Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancer types, and it is associated with a 5‑year survival rate of <10% due to limited early detection methods and ineffective therapeutic options. Thus, an ...
  • Increases in cholecystectomy for gallstone related disease in South Africa 
    Khan, Zafar Ahmed; Khan, Muhammed Uzayr; Brand, Martin (Nature Publishing Group, 2020-08-11)
    Studies suggest that the rate gallstone disease in Africa is low. Previous studies suggested an increase in gallstone rates and cholecystectomies related to urbanization and the adoption of Western lifestyle habits. This ...
  • Inferior vena cava injuries : a case series and review of the South African experience 
    Van Rooyen, P.L.; Karusseit, V.O.L. (Otto); Mokoena, Taole (Elsevier, 2015-01)
    INTRODUCTION : Penetrating injury may involve the major vessels in the abdomen. Injury to the abdominal inferior vena cava (IVC) is uncommon and is usually caused by gunshot wounds. Mortality from IVC injuries is high ...
  • The influence of diabetes mellitus on early outcome following carotid endarterectomy 
    Mulaudzi, Thanyani Victor; Robbs, J.V. (Health and Medical Publishing Group, 2015-03)
    BACKGROUND. There are few studies that look at the influence of diabetes mellitus on early outcome following carotid endarterectomy (CEA). Those available have reported conflicting results, with some showing poor outcome ...
  • Influence of the microbiome metagenomics and epigenomics on gastric cancer 
    Mathebela, Precious; Damane, Botle Precious; Mulaudzi, Thanyani Victor; Mkhize-Khwitshana, Zilungile Lynette; Gaudji, Guy Roger; Dlamini, Zodwa (MDPI, 2022-11)
    Gastric cancer (GC) is one of the major causes of cancer deaths worldwide. The disease is seldomly detected early and this limits treatment options. Because of its heterogeneous and complex nature, the disease remains ...