• Fibrodysplasia ossificans progressiva 

  Smit, Chane; Uys, Andre (Wiley, 2023-11)

  Fibrodysplasia ossificans progressiva is a rare condition with an estimated prevalence of one in two million individuals. The condition is characterized by widespread heterotrophic ossification of skeletal muscles and ...
• An in vitro investigation of l-kynurenine, quinolinic acid, and kynurenic acid on B16 F10 melanoma cell cytotoxicity and morphology 

  Basson, Charlize; Serem, June Cheptoo; Hlophe, Yvette Nkondo; Bipath, Priyesh (Wiley, 2023-10)

  The metastatic behavior of melanoma has accentuated the need for specific therapy targets. Compounds, namely L‐kynurenine (L‐kyn), quinolinic acid (Quin), and kynurenic acid (KA) previously displayed antiproliferative ...
• A new methodology to determine the orifice for root canal configurations in first permanent molar root and canal morphologies using micro-computed tomography 

  Jonker, Casper Hendrik; Lambourn, Guy; Oettle, Anna Catherina; Foschi, Federico; Theye, Charlotte; L'Abbe, Ericka Noelle (MDPI, 2024-01)

  BACKGROUND : The distinction between where the pulp chamber ends and the root canal system begins is poorly defined within the existing literature. METHODS : This paper aimed to describe a range of accurate methods to ...
• Establishing the safety of the lateral femoral cutaneous nerve when using the bridging infix for anterior pelvic fixation 

  Van Schalkwyk, Jerolize; Keough, Natalie; Strydom, Sven; Snyckers, Christian H; Masenge, Andries; Mogale, Nkhensani (MedPharm Publications, 2023-11)

  BACKGROUND Established subcutaneous internal fixation techniques have shown a better quality of life with reduced pain. However, complications still arise, with the most significant being injury of the lateral femoral ...
• Bioactive peptides from African yam (AVIAIMF and GPADPF) and taro (NGDF and NGNW) reveal multifunctional antidiabetic effects using biochemical and cellular models 

  Ibrahim, Mohammed Auwal; Serem, June Cheptoo; Abdullahi, Aliyu Dantani; Aminu, Suleiman; Aliyu, Abubakar Babando; Musa, Aliyu Muhammad; Musa, Bashir; Bester, Megan; Gaspar, A.R.M. (Anabella Regina Marques) (Springer, 2023-04)

  The multifactorial nature of type 2 diabetes mellitus (T2DM) has driven a need to discover multifunctional antidiabetic peptides preferably from functional food sources for possible application as antidiabetic supplements. ...
• Investigation of mandibular second molar root and canal morphology in a Black South African population using cone-beam computed tomography and two classification systems 

  Buchanan, Glynn Dale; Gamieldien, Mohamed Yasin; Fabris-Rotelli, Inger Nicolette; Van Schoor, Albert-Neels; Uys, Andre (Nihon University School of Dentistry, 2023)

  PURPOSE : To investigate the root and canal morphology of mandibular second molars, including anatomical variations, in a Black South African population using two classification systems. METHODS : Cone-beam computed ...
• Veldt fires in South Africa : implications on osteometry and the biological profile 

  Liebenberg, Maritza; Liebenberg, Leandi; Kruger, Gabriele Christa; L'Abbe, Ericka Noelle (Wiley, 2023-03)

  Standard operating procedures for forensic anthropological analyses dictate that thermally altered remains should not be measured, hindering the creation of a biological profile. Few studies have addressed estimating ...
• Creation of 21st century anatomy facilities : designing facilities for integrated preclinical education in the Middle East 

  Lorke, Dietrich E.; Rock, John A.; Hernandez Jr., Robert; Graham, David; Keough, Natalie; Van Tonder, Daniël J. (BMC, 2023-05-26)

  BACKGROUND : The establishment of new anatomy facilities needs to accommodate a combination of modern teaching modalities that best align with evidence-based best teaching practices. This article describes the process ...
• Renal papillary necrosis (RPN) in an African population : disease patterns, relevant pathways, and management 

  Gaudji, Guy Roger; Bida, M.; Conradie, Marius; Damane, Botle Precious; Bester, Megan (MDPI, 2023-01)

  Renal papillary necrosis (RPN) is characterized by coagulative necrosis of the renal medullary pyramids and papillae. Multiple conditions and toxins are associated with RPN. Several RPN risk factors, or POSTCARDS, have ...
• Evaluating postcranial macromorphoscopic traits to estimate population variation among modern South Africans 

  Bothma, Nomshado Pearl; L'Abbe, Ericka Noelle; Liebenberg, Leandi (Elsevier, 2024-03)

  Population overlap and the variation within and among populations have been globally observed but is often difficult to quantify. To achieve this, numerous different methods need to be explored and validated to assist with ...
• Triterpenoids from Protorhus longifolia exhibit hypocholesterolemic potential via regulation of cholesterol biosynthesis and stimulation of low-density lipoprotein uptake in HepG2 cells 

  Ndlovu, Musawenkosi; Mosa, Rebamang; Serem, June Cheptoo; Selepe, Mamoalosi A.; Opoku, Andrew R.; Bester, Megan; Apostolides, Zeno (American Chemical Society, 2023-08-14)

  The increasing incidence of hypercholesterolemia-related diseases even in the presence of the currently available cholesterol-lowering drugs indicates a need to discover new therapeutic drugs. This study aimed to investigate ...
• Surgical treatment is not superior to nonoperative treatment for displaced proximal humerus fractures : a systematic review and meta-analysis 

  Hohmann, Erik; Keough, Natalie; Glatt, Vaida; Tetsworth, Kevin (Elsevier, 2023-05)

  BACKGROUND : The purpose of this study was to perform a systematic review and meta-analysis of both randomized controlled and observational studies comparing conservative to surgical treatment of displaced proximal humerus ...
• Quantifying assays : inhibition of signalling pathways of cancer 

  Anguelov, Roumen; Manjunath, Gandhi; Phiri, Avulundiah Edwin; Nyakudya, Trevor Tapiwa; Bipath, Priyesh; Serem, June Cheptoo; Hlophe, Yvette Nkondo (Oxford University Press, 2023-09)

  Please read abstract in the article.
• The radiologic progression of ameloblastomas 

  Merbold, Lene; Smit, Chane; Ker-Fox, Jason (Health and Medical Publishing Group, 2023-05-31)

  BACKGROUND : In developing countries, many diagnosed cases of ameloblastoma (AB) have a significant delay in receiving treatment because of patient factors and healthcare facility constraints. OBJECTIVES : The radiologic ...
• Covariation between the shape and mineralized tissues of the rib cross section in Homo sapiens, Pan troglodytes and Sts 14 

  Lopez-Rey, Jose M.; Cambra-Moo, Oscar; Martin, Armando Gonzalez; Gonzalez, Nieves Candelas; Sanchez-Andres, Angeles; Tawane, Mirriam; Cazenave, Marine; Williams, Scott A.; Bastir, Markus; Garcia-Martinez, Daniel (Wiley, 2024-01)

  OBJECTIVES : Studying rib torsion is crucial for understanding the evolution of the hominid ribcage. Interestingly, there are variables of the rib cross section that could be associated with rib torsion and, consequently, ...
• Neurophobia : the inconvenient truth 

  Venter, Gerda; Bosman, Marius C.; Lubbe, Johanna (Spanish Association of Anatomy, 2023-09)

  Medical schools have implemented strategies in response to neurophobia to counteract the negative perception and improve neuroscience experiences for undergraduate medical students. In this study, we explored the attitudes, ...
• The surgical anatomy of the axillary approach for nerve transfer procedures targeting the axillary nerve 

  Beytell, Levo; Mennen, Erich; Van Schoor, Albert-Neels; Keough, Natalie (Springer, 2023-05-22)

  PURPOSE : The exact relational anatomy for the anterior axillary approach, targeting the axillary nerve for nerve transfers/ grafts, has not been fully investigated. Therefore, this study aimed to dissect and document the ...
• Adverse neurological effects after exposure to copper, manganese, and mercury mixtures in a Spraque-Dawley rat model : an ultrastructural investigation 

  Draper, Maxine; Bester, Megan; Van Rooy, Mia-Jeanne; Oberholzer, Hester Magdalena (Taylor and Francis, 2023)

  Exposure to environmental metal pollutants is linked to oxidative stress and the subsequent development of neurological disease. In this study, the effects of copper, manganese, and mercury, were evaluated at X100 the World ...
• Decision tree analysis for age estimation in living individuals : integrating cervical and dental radiographic evaluations within a South African population 

  Uys, Andre; Steyn, M.; Botha, D. (Springer, 2024-01)

  Age estimation in living individuals around the age of 18 years is medico-legally important in undocumented migrant cases and in countries like South Africa where many individuals are devoid of identification documents. ...
• Metric evaluation of the anterior nasal spine to estimate sex and population group in South African individuals 

  Davidson, Christy Lana; De Klerk, Johan; Matejovsky, Zina; Fabris-Rotelli, Inger Nicolette; Uys, Andre (Springer, 2024)

  INTRODUCTION : The anterior nasal spine is a pointed, midline projection of the maxilla. This bony structure dictates the overlying soft tissues providing the phenotypic features of the nose and upper lip and determines ...

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