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Browsing by UP Author "Ebenhan, Thomas"
Now showing items 1-20 of 34
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Sathekge, Mike Machaba; Lengana, Thabo; Maes, Alex; Vorster, Mariza; Zeevaart, Jan Rijn; Lawal, Ismaheel Opeyemi; Ebenhan, Thomas; Van de Wiele, Christophe (Springer, 2018-02)PURPOSE : The incidence of prostate cancer is 60% higher and the mortality rate is two- to three-times greater in black versus white men. We report on differences in 68Ga-PSMA-11 PET/CT imaging findings in 77 black ...
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Sathekge, Mike Machaba; Lengana, Thabo; Modiselle, Moshe; Vorster, Mariza; Zeevaart, Jan Rijn; Maes, Alex; Ebenhan, Thomas; Van de Wiele, Christophe (Springer, 2017-04)BACKGROUND : To report on imaging findings using 68Ga-PSMAHBED- CC PET in a series of 19 breast carcinoma patients. METHODS : 68Ga-PSMA-HBED-CC PET imaging results obtained were compared to routinely performed staging ...
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Gouws, Arno Christiaan; Kruger, Hendrik Gerhardus; Gheysens, Olivier; Zeevaart, Jan Rijn; Govender, Thavendran; Naicker, Tricia; Ebenhan, Thomas (Wiley, 2022-11)The excellent features of non-invasive molecular imaging, its progressive technology (real-time, whole-body imaging and quantification), and global impact by a growing infrastructure for positron emission tomography ...
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Ebenhan, Thomas; Gheysens, Olivier; Kruger, Hendrik G.; Zeevaart, Jan Rijn; Sathekge, Mike Machaba (Hindawi Publishing, 2014-08)Antimicrobial peptides (AMPs) are a heterogeneous class of compounds found in a variety of organisms including humans and, so far, hundreds of these structures have been isolated and characterised. They can be described ...
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Suthiram, Janine; Ebenhan, Thomas; Marjanovic-Painter, Biljana; Sathekge, Mike Machaba; Zeevaart, Jan Rijn (MDPI, 2021-08)Please read abstract in the article.
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Le Roux, Jannie; Rubow, Sietke; Ebenhan, Thomas; Wagener, Carl (Springer, 2020-01)Published methods for radiolabelling of 1,4,7-triazacyclononane-1,4,7-triacetic acid ubiquicidin (NOTA-UBI) 29–41 to date describe manual or kit-based procedures. The purpose of this study was to develop an automated ...
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Mdlophane, A.H.; Ebenhan, Thomas; Marjanovic-Painter, B.; Govender, T.; Sathekge, Mike Machaba; Zeevaart, Jan Rijn (Springer, 2019-11)Please read abstract in the article.
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Ankrah, Alfred O.; Lawal, Ismaheel Opeyemi; Boshomane, Tebatso M.G.; Klein, Hans C.; Ebenhan, Thomas; Dierckx, Rudi A.J.O.; Vorster, Mariza; Glaudemans, Andor W.J.M.; Sathekge, Mike Machaba (Thieme Publishing, 2019-09)Please read abstract in the article.
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Le Roux, Jannie; Rubow, Sietske; Ebenhan, Thomas (Elsevier, 2021-02)Gallium-68 labelled 1,4,7-triazacyclononane-1,4,7-triacetic acid ubiquicidin (NOTA-UBI) is currently investigated as a PET radiopharmaceutical for the imaging of infections. The aim of this study was to compare the labelling ...
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Marjanovic-Painter, Biljana; Kleynhans, Janke; Zeevaart, Jan Rijn; Rohwer, Egmont Richard; Ebenhan, Thomas (Elsevier, 2023-01)BACKGROUND : Ubiquicidin is a peptide fragment with selective binding to negatively charged bacterial cell membranes. Besides its earlier labelling with gamma emitting radionuclides, it has been labelled with Positron ...
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Ebenhan, Thomas; Vorster, Mariza; Marjanovic-Painter, Biljana; Wagener, Judith; Suthiram, J.; Modiselle, Moshe; Mokaleng, Botshelo B.; Zeevaart, Jan Rijn; Sathekge, Mike Machaba (MDPI Publishing, 2015-08-14)Prostate-specific membrane antigen (PSMA), a type II glycoprotein, is highly expressed in almost all prostate cancers. By playing such a universal role in the disease, PSMA provides a target for diagnostic imaging of ...
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Ebenhan, Thomas; Schoeman, Isabel; Rossouw, Daniel D.; Grobler, Anne; Marjanovic-Painter, Biljana; Wagener, Judith; Kruger, Hendrik G.; Sathekge, Mike Machaba; Zeevaart, Jan Rijn (Springer, 2017-06)PURPOSE : Radiopharmaceuticals containing the motive tripeptide arginyl-glycyl-asparatic acid (RGD) are known to target ανβ3 integrins during tumor angiogenesis. A more generic kit radiolabeling procedure accommodating ...
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Vorster, Mariza; Modiselle, Moshe; Ebenhan, Thomas; Wagener, Carl; Sello, That; Zeevaart, Jan Rijn; Moshokwa, Evelyn; Sathekge, Mike Machaba (Hellenic Society of Nuclear Medicine, 2015-01)OBJECTIVE : Imaging with fluorine-18-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) has, until recently provided disappointing results with low sensitivity ranging from 31%-64% ...
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Koatale, Palesa Caroline; Welling, Mick M.; Ndlovu, Honest; Kgatle, Mankgopo; Mdanda, Sipho; Mdlophane, Amanda; Okem, Ambrose; Takyi-Williams, John; Sathekge, Mike Machaba; Ebenhan, Thomas (American Chemical Society, 2024-02)The unique structural architecture of the peptidoglycan allows for the stratification of bacteria as either Gram-negative or Gram-positive, which makes bacterial cells distinguishable from mammalian cells. This classification ...
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Lawal, Ismaheel Opeyemi; Vorster, Mariza; Boshomane, Tebatso M.G.; Ololade, Kehinde O.; Ebenhan, Thomas; Sathekge, Mike Machaba (Lippincott Williams and Wilkins, 2015-09)We describe the finding of a metastatic superscan detected by Ga-PSMA PET/CT imaging. A 63-year-old man with metastatic prostate carcinoma underwent Ga-PSMA PET/CT imaging for staging and evaluation of the most appropriate ...
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Microwave-assisted synthesis of meso-carboxyalkyl-BODIPYs and an application to fluorescence imaging Mhlongo, Neliswa Z.; Ebenhan, Thomas; Driver, Cathryn H.S.; Maguire, Glenn E.M.; Kruger, Hendrick G.; Govender, Thavendran; Naicker, Tricia (Royal Society of Chemistry, 2020-10)Please read abstract in the article.
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Duvenhage, Janie; Ebenhan, Thomas; Garny, Seike; Hernández González, Ignacio; Leyva Montana, Rene; Price, Roger; Birkholtz, Lyn-Marie; Zeevaart, Jan Rijn (Springer, 2020-02)Please read abstract in the article.
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Novel receptor tyrosine kinase pathway inhibitors for targeted radionuclide therapy of glioblastoma Bolcaen, Julie; Nair, Shankari; Driver, Cathryn H.S.; Vandevoorde, Charlot; Boshomane, Tebatso M.G.; Ebenhan, Thomas; Vandevoorde, Charlot (MDPI, 2021-06)Glioblastoma (GB) remains the most fatal brain tumor characterized by a high infiltration rate and treatment resistance. Overexpression and/or mutation of receptor tyrosine kinases is common in GB, which subsequently ...
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Kleynhans, Janke; Sathekge, Mike Machaba; Ebenhan, Thomas (MDPI, 2021-08-24)The rationale for application of nanotechnology in targeted alpha therapy (TAT) is sound. However, the translational strategy requires attention. Formulation of TAT in nanoparticulate drug delivery systems has the potential ...
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Ebenhan, Thomas; Chadwick, Nicholas; Sathekge, Mike Machaba; Govender, Patrick; Govender, Thavendran; Kruger, Hendrik G.; Marjanovic-Painter, Biljana; Zeevaart, Jan Rijn (Elsevier, 2014-05)INTRODUCTION: Human antimicrobial peptides are of interest for the development of positron emission tomography (PET) tracers as they exhibit desirable characteristics that make them good candidates for targeting vectors. ...
Now showing items 1-20 of 34